ReviewAdvances in chronic kidney disease2011
Vesicoureteral reflux and reflux nephropathy.
Review in Advances in chronic kidney disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it, 151 citations in OpenAlex.
- The efficacy and safety of corticosteroids in pediatric kidney scar prevention after urinary tract infection: a systematic review and meta-analysis of randomized clinical trials.Pediatric nephrology (Berlin, Germany) · 2023Pooled it
- Dexamethasone to prevent kidney scarring in acute pyelonephritis: a randomized clinical trial.Pediatric nephrology (Berlin, Germany) · 2022Trial
- Renal Scarring in the Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) Trial.Clinical journal of the American Society of Nephrology : CJASN · 2016Trial
- Preoperative predictors for endoscopic Deflux injection therapy for vesicoureteral reflux: a single-center experience during 10 years.Pediatric surgery international · 2026Article
- Urinary tract infections in children.Nature reviews. Urology · 2026Review
- Robotic-assisted laparoscopic ureteral reimplantation using the LUAA technique: VCUG-confirmed outcomes, learning curve and CUSUM analysis.BJUI compass · 2026Article
- Beyond Reflux Grade: Long-Term Outcomes of Children with Grade 1 Vesicoureteral Reflux.Children (Basel, Switzerland) · 2026Article
- Kidney transplantation outcomes in recipients with end-stage kidney disease due to primary vesicoureteral reflux: a case-control study.International urology and nephrology · 2026Article
- Multi-Modal, Machine Learning-Driven Framework Integrating Multi-Omics for Personalized Chronic Kidney Disease Management.Journal of clinical medicine · 2026Review
- Inflammation-Matrix Crosstalk in Vesicoureteral Reflux: Serum and Urinary ECM-Related Biomarkers and Renal Scarring.International journal of molecular sciences · 2026Article
- Does vesicoureteral reflux severity impact breakthrough UTI risk: a multi-institutional analysis and risk stratification.World journal of urology · 2026Article
- Hypertensive retinopathy as a masquerade neuroretinitis in a child: a case report.BMC ophthalmology · 2026Article
- Machine learning-based prediction of vesicoureteral reflux outcomes in infants under antibiotic prophylaxis.Scientific reports · 2025Article
- A Narrative Review of the Evolving Role of Robotic Surgery in Pediatrics: Innovations and Future Prospects.Cureus · 2025Review
- Impact of antibiotic prophylaxis on urinary tract infection recurrence in children Rapid review.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024Review
- Review
- Primary vesicoureteral reflux.Nature reviews. Disease primers · 2024Review
- Multicenter evaluation of complex urinary diversion for renal transplantation: outcomes of complex surgical solutions.World journal of urology · 2024Article
- Suprapubic and Transurethral Bladder Access for Voiding Cystourethrography in Pediatric Male Patients.Pediatric reports · 2024Article
- Risk factors for new renal scarring in children with vesicoureteral reflux receiving continuous antibiotic prophylaxis.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Primary vesicoureteral reflux (VUR) is the commonest congenital urological abnormality in children, which has been associated with an increased risk of urinary tract infection (UTI) and renal scarring, also called reflux nephropathy (RN). In children, RN is diagnosed mostly after UTI (acquired RN) or during follow-up for antenatally diagnosed hydronephrosis with no prior UTI (congenital RN). The acquired RN is more common in female children, whereas the congenital RN is more common in male children. This observation in children might help explain the differences in the clinical presentation of RN in adults, with males presenting mostly with hypertension, proteinuria, and progressive renal failure as compared with females who present mostly with recurrent UTI and have a better outcome. Known risk factors for RN include the severity of VUR, recurrent UTI, and bladder-bowel dysfunction; younger age and delay in treatment of UTI are believed to be other risk factors. Management of VUR is controversial and includes antimicrobial prophylaxis, surgical intervention, or surveillance only. No evidence-based guidelines exist for appropriate follow-up of patients with RN.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.