ReviewDevelopmental and comparative immunology2011
Structural and functional diversity of the lectin repertoire in teleost fish: relevance to innate and adaptive immunity.
Review in Developmental and comparative immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 174 citations in OpenAlex.
- Blood Plasma Proteomic Profiling of Common Carp (Journal of xenobiotics · 2026Article
- Integrated transcriptomic and immune enzymatic analyses uncover coordinated immunometabolic responses in large yellow croaker (Frontiers in immunology · 2025Article
- A "proto" type galectin expressed in striped bass (Frontiers in cellular and infection microbiology · 2025Article
- Article
- Collectin-K1 Plays a Role in the Clearance ofInternational journal of molecular sciences · 2024Article
- CL-K1 Promotes Complement Activation and Regulates Opsonophagocytosis of Macrophages with CD93 Interaction in a Primitive Vertebrate.Journal of immunology (Baltimore, Md. : 1950) · 2024Article
- Proteomic profile of epidermal mucus fromFish and shellfish immunology reports · 2023Article
- The amphibian immune system.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- A Genomic and Transcriptomic Analysis of the C-Type Lectin Gene Family Reveals Highly Expanded and Diversified Repertoires in Bivalves.Marine drugs · 2023Article
- Molecular Cloning and Functional Characterization of Galectin-1 in Yellow Drum (International journal of molecular sciences · 2023Article
- Mannose-binding lectin suppresses macrophage proliferation through TGF-β1 signaling pathway in Nile tilapia.Frontiers in immunology · 2023Article
- Immunological characterization and function analysis of L-type lectin from spotted knifejaw,Frontiers in immunology · 2022Article
- Commensal and Opportunistic Bacteria Present in the Microbiota in Atlantic Cod (Microorganisms · 2021Article
- Molecular Characterization and Functional Analysis of the Nattectin-like Toxin from the Venomous FishToxins · 2021Article
- Ecological Risks Due to Immunotoxicological Effects on Aquatic Organisms.International journal of molecular sciences · 2021Review
- Biochemical Characterization of Oyster and Clam Galectins: Selective Recognition of Carbohydrate Ligands on Host Hemocytes andFrontiers in chemistry · 2020Review
- Fish Galectin8-Like Exerts Positive Regulation on Immune Response Against Bacterial Infection.Frontiers in immunology · 2020Article
- Characterization and Functional Analysis of Two Transmembrane C-Type Lectins in Obscure Puffer (Frontiers in immunology · 2020Article
- Transcription profiles of skin and head kidney from goldfish suffering hemorrhagic septicemia with an emphasis on the TLR signaling pathway.Zoological research · 2019Article
- Functional Aspects of Fish Mucosal Lectins-Interaction with Non-Self.Molecules (Basel, Switzerland) · 2018Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Protein-carbohydrate interactions mediated by lectins have been recognized as key components of innate immunity in vertebrates and invertebrates, not only for recognition of potential pathogens, but also for participating in downstream effector functions, such as their agglutination, immobilization, and complement-mediated opsonization and killing. More recently, lectins have been identified as critical regulators of mammalian adaptive immune responses. Fish are endowed with virtually all components of the mammalian adaptive immunity, and are equipped with a complex lectin repertoire. In this review, we discuss evidence suggesting that: (a) lectin repertoires in teleost fish are highly diversified, and include not only representatives of the lectin families described in mammals, but also members of lectin families described for the first time in fish species; (b) the tissue-specific expression and localization of the diverse lectin repertoires and their molecular partners is consistent with their distinct biological roles in innate and adaptive immunity; (c) although some lectins may bind endogenous ligands, others bind sugars on the surface of potential pathogens; (d) in addition to pathogen recognition and opsonization, some lectins display additional effector roles, such as complement activation and regulation of immune functions; (e) some lectins that recognize exogenous ligands mediate processes unrelated to immunity: they may act as anti-freeze proteins or prevent polyspermia during fertilization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.