ReviewJournal of clinical hypertension (Greenwich, Conn.)2011
PROGRESS: Prevention of Recurrent Stroke.
Review in Journal of clinical hypertension (Greenwich, Conn.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07414732 (The "Savvy for Stroke Survivors" Study), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The "Savvy for Stroke Survivors" Study: Testing a Novel Tool to Help Stroke Survivors Take Their Medication
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019).Hypertension research : official journal of the Japanese Society of Hypertension · 2019Guideline
- Effect of Standard vs Intensive Blood Pressure Control on Cerebral Blood Flow in Small Vessel Disease: The PRESERVE Randomized Clinical Trial.JAMA neurology · 2018Trial
- 2024 Thai guidelines on the treatment of hypertension.Asian biomedicine : research, reviews and news · 2025Article
- Review
- Incidence of First-Ever Stroke, Stroke Events, and Early Case Fatality Rate in China: Results from a National Population-Based Survey.Neuroepidemiology · 2025Article
- Daily blood pressure profile and blood-brain barrier permeability in patients with cerebral small vessel disease.Scientific reports · 2022Article
- Applying Machine Learning to Carotid Sonographic Features for Recurrent Stroke in Patients With Acute Stroke.Frontiers in cardiovascular medicine · 2022Article
- Sex Differences of Combined Effects Between Hypertension and General or Central Obesity on Ischemic Stroke in a Middle-Aged and Elderly Population.Clinical epidemiology · 2021Article
- Hypertension Among Hemorrhagic Stroke Patients in Northeast China: A Population-Based Study 2017-2019.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Use of antihypertensive medication after ischemic stroke in young adults and its association with long-term outcome.Annals of medicine · 2019Article
- Evaluation of a hypertension-based patient education program in a stroke center.International journal of clinical pharmacy · 2018Article
- Racial differences in recurrent ischemic stroke risk and recurrent stroke case fatality.Neurology · 2018Article
- Post-stroke hypertension control and receipt of health care services among veterans.Journal of clinical hypertension (Greenwich, Conn.) · 2018Article
- Angiotensin Receptor Blockade Modulates NFκB and STAT3 Signaling and Inhibits Glial Activation and Neuroinflammation Better than Angiotensin-Converting Enzyme Inhibition.Molecular neurobiology · 2016Article
- Chronic Management of Hypertension after Stroke: The Role of Ambulatory Blood Pressure Monitoring.Journal of stroke · 2016Review
- Trends in vascular risk factor treatment and control in US stroke survivors: the National Health and Nutrition Examination Surveys (1999-2010).Circulation. Cardiovascular quality and outcomes · 2013Article
- Article
- Angiotensin II AT(1) receptor blockers as treatments for inflammatory brain disorders.Clinical science (London, England : 1979) · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Perindopril Protection Against Recurrent Stroke Study (PROGRESS) was a randomized placebo-controlled trial which clearly demonstrated that perindopril-based blood pressure (BP)-lowering treatment is one of the most effective and generalizable strategies for secondary prevention of stroke. Beneficial effects of BP lowering were observed on recurrent stroke, other cardiovascular events, disability, dependency, and cognitive function across a variety of subgroups defined by age, sex, geographical region, body mass index, diabetes, atrial fibrillation, chronic kidney disease, and baseline BP levels. Once patients with stroke have stabilized, all patients should receive BP-lowering therapy irrespective of their BP levels. On the basis of recommendations from current international guidelines, BP should be lowered to <140/90 mm Hg in all patients with cerebrovascular disease and to <130/80 mm Hg if therapy is well tolerated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.