ReviewCurrent opinion in genetics & development2011
Imaging heart development using high-resolution episcopic microscopy.
Review in Current opinion in genetics & development, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed.
- The Conducting Tissues of the Mouse Heart.Journal of cardiovascular development and disease · 2025Article
- The Atrioventricular Conduction Axis in Man and Mouse.Journal of cardiovascular development and disease · 2024Review
- Revisiting the anatomy of the left ventricle in the light of knowledge of its development.Journal of anatomy · 2024Review
- Prognostic value of left ventricular trabeculae fractal analysis in patients with dilated cardiomyopathy.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024Article
- Technologies to Study Genetics and Molecular Pathways.Advances in experimental medicine and biology · 2024Review
- Fractal analysis in cardiovascular magnetic resonance: prognostic value of biventricular trabecular complexity in hypertrophic cardiomyopathy.Cardiovascular diagnosis and therapy · 2023Article
- Three-dimensional microCT imaging of mouse heart development from early post-implantation to late fetal stages.Mammalian genome : official journal of the International Mammalian Genome Society · 2023Review
- Imaging Approaches and the Quantitative Analysis of Heart Development.Journal of cardiovascular development and disease · 2023Review
- Quantitative Image Processing for Three-Dimensional Episcopic Images of Biological Structures: Current State and Future Directions.Biomedicines · 2023Review
- The venous system of E14.5 mouse embryos-reference data and examples for diagnosing malformations in embryos with gene deletions.Journal of anatomy · 2022Article
- Detailed quantification of cardiac ventricular myocardial architecture in the embryonic and fetal mouse heart by application of structure tensor analysis to high resolution episcopic microscopic data.Frontiers in cell and developmental biology · 2022Article
- Iodine-enhanced micro-computed tomography of atherosclerotic plaque morphology complements conventional histology.Atherosclerosis · 2020Article
- Cardiac multi-scale investigation of the right and left ventricleCardiovascular diagnosis and therapy · 2020Review
- Identification and Morphogenesis of Vestibular Atrial Septal Defects.Journal of cardiovascular development and disease · 2020Article
- Quantification of myocardial strain in patients with isolated left ventricular non-compaction and healthy subjects using deformable registration algorithm: comparison with feature tracking.BMC cardiovascular disorders · 2020Article
- High-Resolution Episcopic Imaging for Visualization of Dermal Arteries and Nerves of the Auricular Cymba Conchae in Humans.Frontiers in neuroanatomy · 2020Article
- High-resolution episcopic microscopy enables three-dimensional visualization of plant morphology and development.Plant direct · 2019Article
- Comprehensive Analysis of Animal Models of Cardiovascular Disease using Multiscale X-Ray Phase Contrast Tomography.Scientific reports · 2019Article
- The Fate of the Outflow Tract Septal Complex in Relation to the Classification of Ventricular Septal Defects.Journal of cardiovascular development and disease · 2019Review
- Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function.PloS one · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Development of the heart in vertebrate embryos is a complex process in which the organ is continually remodelled as chambers are formed, valves sculpted and connections established to the developing vascular system. Investigating the genetic programmes driving these changes and the environmental factors that may influence them is critical for our understanding of congenital heart disease. A recurrent challenge in this work is how to integrate studies as diverse as those of cardiac gene function and regulation with an appreciation of the localised interactions between cardiac tissues not to mention the manner in which both may be affected by cardiac function itself. Meeting this challenge requires an accurate way to analyse the changes in 3D morphology of the developing heart, which can be swift or protracted and both dramatic or subtle in consequence. Here we review the use of high-resolution episcopic microscopy as a simple and effective means to examine organ structure and one that allows modern computing methods pioneered by clinical imaging to be applied to the embryonic heart.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.