Evidence map›Paper›PMID 21892744›Full record

ReviewJournal of cardiovascular translational research2011

Biomaterials to prevascularize engineered tissues.

Lei Tian, Steven C George

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of cardiovascular translational research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
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  16. Manipulation of a quasi-natural cell block for high-efficiency transplantation of adherent somatic cells.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2015
    Article
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lei TianThe Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, CA, USA.
Steven C George

Funding

3-D microtissues with perfused human capillariesRC1ES018361 · NIEHS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GEORGE, STEVEN CARL · 2009 to 2010
$996k
Creating a prevascularized thick implantable human tissueR21HL104203 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GEORGE, STEVEN CARL, HUGHES, CHRISTOPHER C. W. · 2010 to 2011
$421k
NHLBI NIH HHS R21 HL104203NIEHS NIH HHS RC1 ES018361
6 · The paper itself

Abstract

Tissue engineering promises to restore tissue and organ function following injury or failure by creating functional and transplantable artificial tissues. The development of artificial tissues with dimensions that exceed the diffusion limit (1-2 mm) will require nutrients and oxygen to be delivered via perfusion (or convection) rather than diffusion alone. One strategy of perfusion is to prevascularize tissues; that is, a network of blood vessels is created within the tissue construct prior to implantation, which has the potential to significantly shorten the time of functional vascular perfusion from the host. The prevascularized network of vessels requires an extracellular matrix or scaffold for 3D support, which can be either natural or synthetic. This review surveys the commonly used biomaterials for prevascularizing 3D tissue engineering constructs.

Indexed as

Biocompatible MaterialsNeovascularization, PhysiologicTissue ScaffoldsAnimalsBlood VesselsCells, CulturedCoculture TechniquesHumansPolymersTime FactorsTissue EngineeringBiocompatible MaterialsPolymers

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.