ArticleNature reviews. Drug discovery2011
Believe it or not: how much can we rely on published data on potential drug targets?
Article in Nature reviews. Drug discovery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 699 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
699 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Good Practice Guideline for Preclinical Alcohol Research: The STRINGENCY Framework.Current topics in behavioral neurosciences · 2025Guideline
- Impact and Assessment of Research Integrity Teaching: A Systematic Literature Review.Science and engineering ethics · 2024Pooled it
- Self-reporting with checklists in artificial intelligence research on medical imaging: a systematic review based on citations of CLAIM.European radiology · 2024Pooled it
- A systematic review of the development and application of home cage monitoring in laboratory mice and rats.BMC biology · 2023Pooled it
- Increasing reproducibility, robustness, and generalizability of biomarker selection from meta-analysis using Bayesian methodology.PLoS computational biology · 2022Pooled it
- Pooled it
- Guidelines for in vivo mouse models of myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2021Guideline
- Assessments of Research Competencies for Clinical Investigators: A Systematic Review.Evaluation & the health professions · 2021Pooled it
- Systematic Review and Meta-analysis of Methodological Quality in In Vivo Animal Studies of Subarachnoid Hemorrhage.Translational stroke research · 2020Pooled it
- Longevity inbioRxiv : the preprint server for biology · 2026Article
- A survey of researchers' attitudes to preregistration in animal research reveals multiple perceived barriers to adoption.PLoS biology · 2026Article
- Transient Middle Cerebral Artery Occlusion in Rats as a Nonclinical Model of Ischemic Stroke: A Systematic Review.Current issues in molecular biology · 2026Review
- Impact of regularization methods and outlier removal on unsupervised sample classification.BMC bioinformatics · 2026Article
- Evaluation of the replicability of systematic reviews with meta-analyses of the effects of health interventions.Research synthesis methods · 2026Article
- CODE beyond FAIR: a roadmap for reusable research software.Scientific data · 2026Article
- Examination of Replicate Syntheses of Metal Organic Frameworks as a Window into Reproducibility in Materials Chemistry.The journal of physical chemistry. C, Nanomaterials and interfaces · 2026Review
- From Core Facility to Collaborative Partner: Reimagining Institutional Shared Resources as CRO-Model Research Partners Enhanced by Agentic AI.Journal of biomolecular techniques : JBT · 2026Review
- Human Induced Pluripotent Stem Cells in Rare Neurological Disorders: Opportunities and Challenges for Disease Modeling and Drug Discovery.Stem cells international · 2026Review
- Need for NAMs: A systematic evidence synthesis revealing over half a century of drug development failure.NAM journal · 2026Article
- Advancements in nanomedicines for cancer therapy: targeting molecular signaling pathways, activating immune cells, and using photothermal immunomodulation.Frontiers in bioengineering and biotechnology · 2026Review
639 more citing papers are in PubMed but not listed here.
Corrections and comments
- Comment on
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
21892149What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.