ArticleJournal of the American Society of Hypertension : JASH
Association of self-reported race/ethnicity and genetic ancestry with arterial elasticity: the Multi-Ethnic Study of Atherosclerosis (MESA).
Article in Journal of the American Society of Hypertension : JASH. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Whole genome sequencing of 1427 Mexican individuals from the oriGen cohort.Nature communications · 2026Article
- Thoracic Aortic Volume as a Predictor of Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis.Journal of magnetic resonance imaging : JMRI · 2024Article
- Association ofJournal of the American Heart Association · 2020Article
- Arterial elasticity as a risk factor for early cardiovascular disease among testicular cancer survivors treated with platinum-based chemotherapy: a cross-sectional pilot study.Vascular health and risk management · 2018Article
- Race-Related Differences in Left Ventricular Structural and Functional Remodeling in Response to Increased Afterload: The ARIC Study.JACC. Heart failure · 2017Article
- Differences in galectin-3, a biomarker of fibrosis, between participants with peripheral artery disease and participants with normal ankle-brachial index.Vascular medicine (London, England) · 2016Article
- NAFLD prevalence differs among hispanic subgroups: the Multi-Ethnic Study of Atherosclerosis.World journal of gastroenterology · 2014Article
- NOS1 methylation and carotid artery intima-media thickness in children.Circulation. Cardiovascular genetics · 2014Article
- Race, genetic ancestry and response to antidepressant treatment for major depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2013Article
- No association of 9p21 with arterial elasticity and retinal microvascular findings.Atherosclerosis · 2013Article
- Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004.Arthritis and rheumatism · 2013Article
- A review of genetics, arterial stiffness, and blood pressure in African Americans.Journal of cardiovascular translational research · 2012Review
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
African Americans have a disproportionate burden of hypertension compared with white, whereas data on Hispanics is less well-defined. Mechanisms underlying these differences are unclear, but could be in part because of ancestral background and vascular function. We studied 660 African Americans and 635 Hispanics from the Multi-Ethnic Study of Atherosclerosis (MESA) with complete data on genetic ancestry, pulse pressure (PP), and large and small arterial elasticity (LAE, SAE). LAE and SAE were obtained using the HDI PulseWave CR-2000 Research CardioVascular Profiling Instrument. Among African Americans, higher European ancestry was marginally associated with higher LAE (P = .05) and lower PP (P = .05); results for LAE were attenuated after adjustment for potential mediators (P = .30). Among Hispanics, higher Native American ancestry was associated with higher SAE (P = .0006); higher African ancestry was marginally associated with lower SAE (P = .07). Ancestry was not significantly associated with LAE or PP in Hispanics. Among African Americans, higher European ancestry may be associated with less large artery damage, as measured by LAE and PP, although these associations warrant further study. Among Hispanics, ancestry is strongly associated with SAE. Future studies should consider genetic ancestry when studying hypertension in race/ethnic minorities, particularly among Hispanics.
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