Evidence map›Paper›PMID 21890064›Full record

ReviewTicks and tick-borne diseases2011

Updates on Borrelia burgdorferi sensu lato complex with respect to public health.

Nataliia Rudenko, Maryna Golovchenko, Libor Grubhoffer, James H Oliver

Abstract readReview
In one paragraph

Review in Ticks and tick-borne diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 157 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
157citing papers in PubMed, 2 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

157 citing papers in PubMed, 2 syntheses or guidelines pooled it, 328 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Predicting Lyme Disease: A One Health Approach.Pathogens (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. The First Study ofPathogens (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Silent Spread ofHealthcare (Basel, Switzerland) · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

97 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Nataliia RudenkoBiology Centre AS CR v.v.i. AS CR, Institute of Parasitology, Branisovska 31, 37005 Ceske Budejovice, Czech Republic. natasha@paru.cas.cz
Maryna Golovchenko
Libor Grubhoffer
James H Oliver
Georgia Southern University · USUniversity of South Bohemia in České Budějovice · CZ

Funding

IXODES TICKS AND BORRELIA BURGDORFERI IN SE USAR37AI024899 · NIAID · GEORGIA SOUTHERN UNIVERSITY · PI OLIVER, JAMES H · 1996 to 2005
$1.7M
NIAID NIH HHS R37 AI024899NIAID NIH HHS R37AI-24899PHS HHS U50/CCU410282
6 · The paper itself

Abstract

Borrelia burgdorferi sensu lato (s.l.) complex is a diverse group of worldwide distributed bacteria that includes 18 named spirochete species and a still not named group proposed as genomospecies 2. Descriptions of new species and variants continue to be recognized, so the current number of described species is probably not final. Most of known spirochete species are considered to have a limited distribution. Eleven species from the B. burgdorferi s.l. complex were identified in and strictly associated with Eurasia (B. afzelii, B. bavariensis, B. garinii, B. japonica, B. lusitaniae, B. sinica, B. spielmanii, B. tanukii, B. turdi, B. valaisiana, and B. yangtze), while another 5 (B. americana, B. andersonii, B. californiensis, B. carolinensis, and B. kurtenbachii) were previously believed to be restricted to the USA only. B. burgdorferi sensu stricto (s.s.), B. bissettii, and B. carolinensis share the distinction of being present in both the Old and the New World. Out of the 18 genospecies, 3 commonly and 4 occasionally infect humans, causing Lyme borreliosis (LB) - a multisystem disease that is often referred to as the 'great imitator' due to diversity of its clinical manifestations. Among the genospecies that commonly infect people, i.e. B. burgdorferi s.s., B. afzelii, and B. garinii, only B. burgdorferi s.s. causes LB both in the USA and in Europe, with a wide spectrum of clinical conditions ranging from minor cutaneous erythema migrans (EM) to severe arthritis or neurological manifestations. The epidemiological data from many European countries and the USA show a dramatic increase of the diagnosed cases of LB due to the development of new progressive diagnostic methods during the last decades (Hubálek, 2009). Recently, the definition of the disease has also changed. What was not considered Lyme borreliosis before might be now.

Indexed as

Lyme DiseaseAnimalsArachnid VectorsAsiaBacterial Typing TechniquesBirdsBorrelia burgdorferiDisease ReservoirsDNA, BacterialEuropeGenetic VariationHumansPhylogenyPhylogeographyPolymerase Chain ReactionPublic HealthDNA, Bacterial

Identifiers

PMID21890064
PMCPMC3167092
OpenAlexW2002952652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.