ReviewEndocrinology and metabolism clinics of North America2011
Estrogens and prostate cancer: etiology, mediators, prevention, and management.
Review in Endocrinology and metabolism clinics of North America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 53 citations in OpenAlex.
- Dysregulation of estrogen signaling and HSD17B7 in the prostate stroma of African American men.Endocrinology · 2026Article
- The Pros and Cons of Estrogens in Prostate Cancer: An Update with a Focus on Phytoestrogens.Biomedicines · 2024Review
- The Role of Microbial Factors in Prostate Cancer Development-An Up-to-Date Review.Journal of clinical medicine · 2021Review
- The 3,4-Quinones of Estrone and Estradiol Are the Initiators of Cancer whereas Resveratrol andInternational journal of molecular sciences · 2021Review
- Effects of Dietary Phytoestrogens on Hormones throughout a Human Lifespan: A Review.Nutrients · 2020Review
- Serum Omentin Levels in Patients with Prostate Cancer and Associations with Sex Steroids and Metabolic Syndrome.Journal of clinical medicine · 2020Article
- Prognostic factors of survival in patients with malignant pleural mesothelioma: an analysis of the National Cancer Database.Carcinogenesis · 2019Article
- Estrogens and prostate cancer.Prostate cancer and prostatic diseases · 2019Review
- Comparability of serum, plasma, and urinary estrogen and estrogen metabolite measurements by sex and menopausal status.Cancer causes & control : CCC · 2019Article
- Bisphenol A and its analogues disrupt centrosome cycle and microtubule dynamics in prostate cancer.Endocrine-related cancer · 2017Article
- Molecular mechanisms involving prostate cancer racial disparity.American journal of clinical and experimental urology · 2017Review
- Estrogen Exhibits a Biphasic Effect on Prostate Tumor Growth through the Estrogen Receptor β-KLF5 Pathway.Molecular and cellular biology · 2016Article
- Risk of Sex-Specific Cancers in Opposite-Sex and Same-Sex Twins in Denmark and Sweden.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015Article
- Estrogen modulation of the ethanol-evoked myocardial oxidative stress and dysfunction via DAPK3/Akt/ERK activation in male rats.Toxicology and applied pharmacology · 2015Article
- Hsa-miRNA-765 as a key mediator for inhibiting growth, migration and invasion in fulvestrant-treated prostate cancer.PloS one · 2014Article
- Targeting GPR30 with G-1: a new therapeutic target for castration-resistant prostate cancer.Endocrine-related cancer · 2014Article
- In vitro chronic administration of ERbeta selective ligands and prostate cancer cell growth: hypotheses on the selective role of 3beta-adiol in AR-positive RV1 cells.BioMed research international · 2014Article
- A novel role for raloxifene nanomicelles in management of castrate resistant prostate cancer.BioMed research international · 2014Article
- Estrogen receptor β (ERβ1) transactivation is differentially modulated by the transcriptional coregulator Tip60 in a cis-acting element-dependent manner.The Journal of biological chemistry · 2013Article
- Differential expression of estrogen receptor beta isoforms in prostate cancer through interplay between transcriptional and translational regulation.Molecular and cellular endocrinology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The mainstay targets for hormonal prostate cancer (PCa) therapies are based on negating androgen action. Recent epidemiologic and experimental data have pinpointed the key roles of estrogens in PCa development and progression. Racial and geographic differences, as well as age-associated changes, in estrogen synthesis and metabolism contribute significantly to the etiology. This article summarizes how different estrogens/antiestrogens/estrogen mimics contribute to prostate carcinogenesis, the roles of the different mediators of estrogen in the process, and the potentials of new estrogenic/antiestrogenic compounds for prevention and treatment of PCa.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.