Evidence map›Paper›PMID 21889436›Full record

SynthesisClinical psychology review2011

Genetic and environmental influences on impulsivity: a meta-analysis of twin, family and adoption studies.

Serena Bezdjian, Laura A Baker, Catherine Tuvblad

Abstract readMeta-Analysis
In one paragraph

Synthesis in Clinical psychology review, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Serena BezdjianWashington University School of Medicine, USA. bezdjian@usc.edu
Laura A Baker
Catherine Tuvblad

Funding

RISK FACTORS FOR ANTISOCIAL BEHAVIORR01MH058354 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BAKER, LAURA A · 2000 to 2013
$8.5M
T32 Training Grant in Epidemiology, Services and Prevention ResearchT32DA007313 · NIDA · WASHINGTON UNIVERSITY · PI PRICE, RUMI KATO · 1999 to 2013
$2.9M
Heritability of Impulsivity during the Go/NoGo TaskF31MH068953 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BEZDJIAN, SERENA · 2005 to 2007
$130k
NIDA NIH HHS T32 DA007313NIDA NIH HHS T32 DA07313NIMH NIH HHS F31 MH068953NIMH NIH HHS R01 MH058354NIMH NIH HHS R01 MH58354
6 · The paper itself

Abstract

A meta-analysis of twin, family and adoption studies was conducted to estimate the magnitude of genetic and environmental influences on impulsivity. The best fitting model for 41 key studies (58 independent samples from 14 month old infants to adults; N=27,147) included equal proportions of variance due to genetic (0.50) and non-shared environmental (0.50) influences, with genetic effects being both additive (0.38) and non-additive (0.12). Shared environmental effects were unimportant in explaining individual differences in impulsivity. Age, sex, and study design (twin vs. adoption) were all significant moderators of the magnitude of genetic and environmental influences on impulsivity. The relative contribution of genetic effects (broad sense heritability) and unique environmental effects were also found to be important throughout development from childhood to adulthood. Total genetic effects were found to be important for all ages, but appeared to be strongest in children. Analyses also demonstrated that genetic effects appeared to be stronger in males than in females. Method of assessment (laboratory tasks vs. questionnaires), however, was not a significant moderator of the genetic and environmental influences on impulsivity. These results provide a structured synthesis of existing behavior genetic studies on impulsivity by providing a clearer understanding of the relative genetic and environmental contributions in impulsive traits through various stages of development.

Indexed as

Social EnvironmentAdoptionFamilyFemaleHumansImpulsive BehaviorMaleTwinsTwin Studies as Topic

Identifiers

PMID21889436
PMCPMC3176916

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.