Evidence map›Paper›PMID 21888789›Full record

ArticleEmerging infectious diseases2011

Increasing incidence of invasive Haemophilus influenzae disease in adults, Utah, USA.

Matthew P Rubach, Jeffrey M Bender, Susan Mottice, Kimberly Hanson, Hsin Y C Weng, Kent Korgenski, Judy A Daly, Andrew T Pavia

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Changing Landscape ofCase reports in infectious diseases · 2024
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  3. World journal of oncology · 2023
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  7. Review
  8. Review
  9. Article
  10. Non-TypeableInternational journal of molecular sciences · 2020
    Article
  11. Molecular epidemiology of invasive Haemophilus influenzae disease in Portugal: an update of the post-vaccine period, 2011-2018.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Developing a vaccine forCanada communicable disease report = Releve des maladies transmissibles au Canada · 2017
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Matthew P RubachUniversity of Utah, Salt Lake City, Utah, USA. matthew.rubach@duke.edu
Jeffrey M Bender
Susan Mottice
Kimberly Hanson
Hsin Y C Weng
Kent Korgenski
Judy A Daly
Andrew T Pavia
University of Utah · US

Funding

FilmArray Biothreat Pathogens: An Automated Multiplex PCR Diagnostic SystemU01AI082184 · NIAID · BIOFIRE DEFENSE, LLC. · PI OTA, IRENE M · 2009 to 2010
$3.0M
Epidemiology and Etiology of Hospitalized Pneumonia in ChildrenU18IP000303 · IP · UNIVERSITY OF UTAH · PI AMPOFO, KROW · 2009 to 2010
$1.6M
NCIRD CDC HHS U18 IP000303NCIRD CDC HHS U18-IP000303-01NIAID NIH HHS U01 AI082184NIAID NIH HHS U01AI082184-01
6 · The paper itself

Abstract

Since the introduction of the Haemophilus influenzae type b vaccine, the incidence of invasive H. influenzae type b disease among children has fallen dramatically, but the effect on invasive H. influenzae disease among adults may be more complex. In this population-based study we examined the epidemiology and outcomes of invasive disease caused by typeable and nontypeable H. influenzae among Utah adults during 1998-2008. The overall incidence increased over the study period from 0.14/100,000 person-years in 1998 to 1.61/100,000 person-years in 2008. The average incidence in persons >65 years old was 2.74/100,000 person-years, accounting for 51% of cases and 67% of deaths. The incidence was highest for nontypeable H. influenzae (0.23/100,000 person-years), followed by H. influenzae type f (0.14/100,000 person-years). The case-fatality rate was 22%. The incidence of invasive H. influenzae in Utah adults appears to be increasing. Invasive H. influenzae infection disproportionately affected the elderly and was associated with a high mortality rate.

Indexed as

AdolescentAdultAgedBacteremiaHaemophilus InfectionsHaemophilus influenzaeHumansIncidenceMeningitis, HaemophilusMiddle AgedSerotypingUtahYoung Adult

Identifiers

PMID21888789
PMCPMC3322072
OpenAlexW1980887844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.