ArticleEmerging infectious diseases2011
Estimating effect of antiviral drug use during pandemic (H1N1) 2009 outbreak, United States.
Article in Emerging infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.The Lancet. Respiratory medicine · 2014Pooled it
- Impact of neuraminidase inhibitor treatment on outcomes of public health importance during the 2009-2010 influenza A(H1N1) pandemic: a systematic review and meta-analysis in hospitalized patients.The Journal of infectious diseases · 2013Pooled it
- Neuraminidase inhibitors for influenza: a review and public health perspective in the aftermath of the 2009 pandemic.Influenza and other respiratory viruses · 2013Pooled it
- Diagnostic Accuracy of the Quidel Sofia Rapid Influenza Fluorescent Immunoassay in Patients with Influenza-like Illness: A Systematic Review and Meta-analysis.Tuberculosis and respiratory diseases · 2021Article
- Timely Antiviral Administration During an Influenza Pandemic: Key Components.American journal of public health · 2018Article
- Influenza in Asthmatics: For Better or for Worse?Frontiers in immunology · 2018Review
- Synergistic effects of influenza and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) can be eliminated by the use of influenza therapeutics: experimental evidence for the multi-hit hypothesis.NPJ Parkinson's disease · 2017Article
- Neuraminidase inhibitor therapy in a military population.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2015Article
- Assessing the use of antiviral treatment to control influenza.Epidemiology and infection · 2015Article
- Estimating the United States demand for influenza antivirals and the effect on severe influenza disease during a potential pandemic.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015Article
- Optimizing distribution of pandemic influenza antiviral drugs.Emerging infectious diseases · 2015Article
- Discovering Multi-Scale Co-Occurrence Patterns of Asthma and Influenza with Oak Ridge Bio-Surveillance Toolkit.Frontiers in public health · 2015Article
- Impact of medical and behavioural factors on influenza-like illness, healthcare-seeking, and antiviral treatment during the 2009 H1N1 pandemic: USA, 2009-2010.Epidemiology and infection · 2014Article
- Oseltamivir use and outcomes during the 2009 influenza A H1N1 pandemic in Taiwan.BMC public health · 2013Observational
- Public health management of antiviral drugs during the 2009 H1N1 influenza pandemic: a survey of local health departments in California.BMC public health · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
From April 2009 through March 2010, during the pandemic (H1N1) 2009 outbreak, ≈8.2 million prescriptions for influenza neuraminidase-inhibiting antiviral drugs were filled in the United States. We estimated the number of hospitalizations likely averted due to use of these antiviral medications. After adjusting for prescriptions that were used for prophylaxis and personal stockpiles, as well as for patients who did not complete their drug regimen, we estimated the filled prescriptions prevented ≈8,400-12,600 hospitalizations (on the basis of median values). Approximately 60% of these prevented hospitalizations were among adults 18-64 years of age, with the remainder almost equally divided between children 0-17 years of age and adults >65 years of age. Public health officials should consider these estimates an indication of success of treating patients during the 2009 pandemic and a warning of the need for renewed planning to cope with the next pandemic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.