Evidence map›Paper›PMID 21888650›Full record

ReviewVeterinary research2011

Antimicrobial peptides and proteins of the horse--insights into a well-armed organism.

Oliver Bruhn, Joachim Grötzinger, Ingolf Cascorbi, Sascha Jung

Open access · goldAbstract readReview
In one paragraph

Review in Veterinary research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Frontiers in immunology · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Insights on Health and Food Applications ofFoods (Basel, Switzerland) · 2020
    Review
  17. What Is the Evolutionary Fingerprint in Neutrophil Granulocytes?International journal of molecular sciences · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Oliver BruhnInstitute for Experimental and Clinical Pharmacology, Hospitalstraße 4, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany. obruhn@pharmakologie.uni-kiel.de.
Joachim Grötzinger
Ingolf Cascorbi
Sascha Jung
Kiel University · DEUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with different specificities and potencies depending on the structure and amino-acid composition of the peptides. Several antimicrobial peptides were comprehensively investigated in the last three decades and some molecules with remarkable antimicrobial properties have reached the third phase of clinical studies. Next to the peptides themselves, numerous organisms were examined and analyzed regarding their repertoire of antimicrobial peptides revealing a huge number of candidates with potencies and properties for future medical applications. One of these organisms is the horse, which possesses numerous peptides that are interesting candidates for therapeutical applications in veterinary medicine. Here we summarize investigations and knowledge on equine antimicrobial peptides, point to interesting candidates, and discuss prospects for therapeutical applications.

Indexed as

Gene Expression RegulationAmino Acid MotifsAmino Acid SequenceAnimalsAnti-Infective AgentsAntimicrobial Cationic PeptidesHorse DiseasesHorsesOrgan SpecificitySequence AlignmentAnti-Infective AgentsAntimicrobial Cationic Peptides

Identifiers

PMID21888650
PMCPMC3179947
OpenAlexW2139601739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.