ReviewCurrent opinion in virology2011
Viral life cycles captured in three-dimensions with electron microscopy tomography.
Review in Current opinion in virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Algal Viruses: The (Atomic) Shape of Things to Come.Viruses · 2018Review
- Electron cryomicroscopy as a powerful tool in biomedical research.Journal of molecular medicine (Berlin, Germany) · 2018Review
- New insights into rotavirus entry machinery: stabilization of rotavirus spike conformation is independent of trypsin cleavage.PLoS pathogens · 2014Article
- A cool hybrid approach to the herpesvirus 'life' cycle.Current opinion in virology · 2014Review
- Virus morphogenesis in the cell: methods and observations.Sub-cellular biochemistry · 2013Review
- Virus factories: biogenesis and structural design.Cellular microbiology · 2013Review
- Impact on the endoplasmic reticulum and Golgi apparatus of turnip mosaic virus infection.Journal of virology · 2012Article
- Putting structure into context: fitting of atomic models into electron microscopic and electron tomographic reconstructions.Current opinion in cell biology · 2012Review
- Virus disinfection mechanisms: the role of virus composition, structure, and function.Current opinion in virology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Viruses hijack host cell functions and optimize them for viral replication causing a severe threat to human health. However, viruses are also tools to understand cell biology and they may be effective reagents in nano-medicine. Studies from the molecular to cellular levels are aimed at understanding the details of viral life cycles and the underlying virus-host interactions. Recent developments in electron microscopy tomography allow viral and cellular events to be observed in fine structural detail in three-dimension. By combining high-resolution structures of individual proteins and macro-complexes obtained by crystallography and electron cryo-microscopy and image reconstruction with reconstructions performed on sub-tomographic volumes, electron tomography has advanced the structural and mechanistic understanding of virus infections both in vitro and in host cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.