Evidence map›Paper›PMID 21886944›Full record

ArticleJournal of micromechanics and microengineering : structures, devices, and systems2011

MEMS Sensors and Microsystems for Cell Mechanobiology.

Jagannathan Rajagopalan, M Taher A Saif

Open access · greenAbstract read
In one paragraph

Article in Journal of micromechanics and microengineering : structures, devices, and systems, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 73 citations in OpenAlex.

  1. Review
  2. Review
  3. Harnessing mechanobiology for kidney organoid research.Frontiers in cell and developmental biology · 2023
    Review
  4. Review
  5. Review
  6. Article
  7. Manipulation of Axonal Outgrowth via Exogenous Low Forces.International journal of molecular sciences · 2020
    Review
  8. Review
  9. Review
  10. Article
  11. An Integrated Cytoskeletal Model of Neurite Outgrowth.Frontiers in cellular neuroscience · 2018
    Review
  12. Review
  13. Quantifying forces in cell biology.Nature cell biology · 2017
    Review
  14. Review
  15. Quantifying mechanical force in axonal growth and guidance.Frontiers in cellular neuroscience · 2015
    Review
  16. Article
  17. Article
  18. The mechanobiology of brain function.Nature reviews. Neuroscience · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jagannathan RajagopalanDepartment of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 W Green Street Urbana IL -61801 USA jrajago2@illinois.edu , saif@illinois.edu.
M Taher A Saif
University of Illinois Urbana-Champaign · US

Funding

Mechanical Force and Neural RegenerationR01NS063405 · NINDS · UNIVERSITY OF MIAMI CORAL GABLES · PI CHIBA, AKIRA, JAKOBSSON, ERIC G · 2008 to 2011
$1.2M
NINDS NIH HHS R01 NS063405
6 · The paper itself

Abstract

Forces generated by cells play a vital role in many cellular processes like cell spreading, motility, differentiation and apoptosis. Understanding the mechanics of single cells is essential to delineate the link between cellular force generation/sensing and function. MEMS sensors, because of their small size and fine force/displacement resolution, are ideal for force and displacement sensing at the single cell level. In addition, the amenability of MEMS sensors to batch fabrication methods allows the study of large cell populations simultaneously, leading to robust statistical studies. In this review, we discuss various microsystems used for studying cell mechanics and the insights on cell mechanical behavior that have resulted from their use. The advantages and limitations of these microsystems for biological studies are also outlined.

Identifiers

PMID21886944
PMCPMC3163288
OpenAlexW2140707093

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.