ArticlePLoS neglected tropical diseases2011
Diagnosis, clinical features, and self-reported morbidity of Strongyloides stercoralis and hookworm infection in a Co-endemic setting.
Article in PLoS neglected tropical diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.
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Who cites it
55 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Strongyloides stercoralis-hookworms association as a path to the estimation of the global burden of strongyloidiasis: A systematic review.PLoS neglected tropical diseases · 2020Pooled it
- Economic evaluations of human schistosomiasis interventions: a systematic review and identification of associated research needs.Wellcome open research · 2020Pooled it
- Morbidity Associated with ChronicThe American journal of tropical medicine and hygiene · 2019Pooled it
- Rapid re-infection with soil-transmitted helminths after triple-dose albendazole treatment of school-aged children in Yunnan, People's Republic of China.The American journal of tropical medicine and hygiene · 2013Trial
- Strongyloidiasis as a Focal Household Cluster of Soil-Transmitted Helminthiasis in Rural Tropical Rainforest Southern Thailand: An Observational Study.Scientifica · 2026Article
- Review
- Strongyloides stercoralis, but Not Hookworm, First-Stage Larvae Require Stool-Soluble Components for Growth and Development.The American journal of tropical medicine and hygiene · 2025Article
- Case Report: Endoscopic examination improves the diagnosis of inconspicuous helminth infections in adults in Shanghai.Frontiers in medicine · 2025Article
- A 5-year single-center review ofProceedings (Baylor University. Medical Center) · 2025Article
- Comparison of parasitological methods for the identification of soil-transmitted helminths, includingParasite epidemiology and control · 2024Article
- Strongyloidiasis.Nature reviews. Disease primers · 2024Review
- A comparative 'omics' approach for prediction of candidate Strongyloides stercoralis diagnostic coproantigens.PLoS neglected tropical diseases · 2023Article
- Seroepidemiology of Strongyloides spp. Infection in Balimo, Western Province, Papua New Guinea.The American journal of tropical medicine and hygiene · 2023Article
- Perceived water-related risk factors of Buruli ulcer in two villages of south-central Côte d'Ivoire.PLoS neglected tropical diseases · 2022Article
- Article
- Article
- An optimized agar plate culture improves diagnostic efficiency for Strongyloides stercoralis infection in an endemic community.Parasitology research · 2020Article
- Solid organ transplantation in older adults. Infectious and other age-related considerations.OBM transplantation · 2019Article
- Strongyloides stercoralis: Spatial distribution of a highly prevalent and ubiquitous soil-transmitted helminth in Cambodia.PLoS neglected tropical diseases · 2019Article
- Characterization of a non-sexual population of Strongyloides stercoralis with hybrid 18S rDNA haplotypes in Guangxi, Southern China.PLoS neglected tropical diseases · 2019Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfections with Strongyloides stercoralis and other helminths represent important, yet often neglected issues in developing countries. Indeed, strongyloidiasis can be fatal, but only a few studies provide information regarding its health relevance in Africa. Moreover, clinical data on symptomatology and typical recognition patterns mainly originate from Western travel clinics. METHODOLOGY: A cross-sectional epidemiological survey was carried out in a rural part of south-central Côte d'Ivoire. Stool samples from 292 randomly selected individuals were examined for intestinal helminths, using a suite of diagnostic techniques (i.e., Kato-Katz, Baermann funnel, and Koga agar plate). Participants were interviewed with a pre-tested questionnaire and clinically examined. Multivariate logistic regression analysis was done to relate perceived morbidity and clinical findings to helminth infection status. PRINCIPAL
findingsThe prevalence of hookworm and S. stercoralis was 51.0% and 12.7%, respectively. Both infections were strongly associated with each other (adjusted odds ratio, 6.73; P < 0.001) and higher prevalences were observed with age. S. stercoralis-infected individuals expressed self-reported morbidity considerably more often than those with hookworm infection. Clinical examination identified high prevalences of various pathologies and detected tendencies to worse health conditions in helminth-infected subjects. CONCLUSIONS/SIGNIFICANCE: The use of multiple diagnostic tools showed that S. stercoralis and hookworm are co-endemic in rural Côte d'Ivoire and that each infection causes clinical symptoms and sequelae. Our findings are important for (re-)estimating the burden of helminth infections, and highlight the need for integrating epidemiological surveys, rigorous diagnostic approaches, and clinical assessments in the developing world.
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