ArticlePloS one2011
A plant DJ-1 homolog is essential for Arabidopsis thaliana chloroplast development.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 46 citations in OpenAlex.
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- Mining the cucumber core collection: phenotypic and genetic characterization of morphological diversity for fruit quality characteristics.Horticulture research · 2025Article
- Proteomics- and metabolomics-based analysis of the regulation of germination in Norway maple and sycamore embryonic axes.Tree physiology · 2025Article
- Global impacts of peroxisome and pexophagy dysfunction revealed through multi-omics analyses of lon2 and atg2 mutants.The Plant journal : for cell and molecular biology · 2024Article
- Albino lethal 13, a chloroplast-imported protein required for chloroplast development in rice.Plant direct · 2024Article
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- Comparative Transcriptome Analysis Reveals Novel Candidate Resistance Genes Involved in Defence againstInternational journal of molecular sciences · 2023Article
- The Tale of DJ-1 (PARK7): A Swiss Army Knife in Biomedical and Psychological Research.International journal of molecular sciences · 2023Review
- Oxidative and Glycation Damage to Mitochondrial DNA and Plastid DNA during Plant Development.Antioxidants (Basel, Switzerland) · 2023Review
- Elevated inorganic carbon and salinity enhances photosynthesis and ATP synthesis in picoalgaFrontiers in microbiology · 2023Article
- Glyoxalase I activity affects Arabidopsis sensitivity to ammonium nutrition.Plant cell reports · 2022Article
- Proteomics Evidence of a Systemic Response to Desiccation in the Resurrection PlantInternational journal of molecular sciences · 2022Article
- Glycation damage to organelles and their DNA increases during maize seedling development.Scientific reports · 2022Article
- Protein-protein interactions in plant antioxidant defense.Frontiers in plant science · 2022Review
- Tracing the Evolution of Plant Glyoxalase III Enzymes for Structural and Functional Divergence.Antioxidants (Basel, Switzerland) · 2021Article
- Association genetics of the parameters related to nitrogen use efficiency in Brassica juncea L.Plant molecular biology · 2021Article
- Unusual DNA-binding properties of the Arabidopsis thaliana WRKY50 transcription factor at target gene promoters.Plant cell reports · 2021Article
- FLOURY ENDOSPERM15 encodes a glyoxalase I involved in compound granule formation and starch synthesis in rice endosperm.Plant cell reports · 2019Article
- Bifunctional Chloroplastic DJ-1B fromAntioxidants (Basel, Switzerland) · 2019Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Protein superfamilies can exhibit considerable diversification of function among their members in various organisms. The DJ-1 superfamily is composed of proteins that are principally involved in stress response and are widely distributed in all kingdoms of life. The model flowering plant Arabidopsis thaliana contains three close homologs of animal DJ-1, all of which are tandem duplications of the DJ-1 domain. Consequently, the plant DJ-1 homologs are likely pseudo-dimeric proteins composed of a single polypeptide chain. We report that one A. thaliana DJ-1 homolog (AtDJ1C) is the first DJ-1 homolog in any organism that is required for viability. Homozygous disruption of the AtDJ1C gene results in non-viable, albino seedlings that can be complemented by expression of wild-type or epitope-tagged AtDJ1C. The plastids from these dj1c plants lack thylakoid membranes and granal stacks, indicating that AtDJ1C is required for proper chloroplast development. AtDJ1C is expressed early in leaf development when chloroplasts mature, but is downregulated in older tissue, consistent with a proposed role in plastid development. In addition to its plant-specific function, AtDJ1C is an atypical member of the DJ-1 superfamily that lacks a conserved cysteine residue that is required for the functions of most other superfamily members. The essential role for AtDJ1C in chloroplast maturation expands the known functional diversity of the DJ-1 superfamily and provides the first evidence of a role for specialized DJ-1-like proteins in eukaryotic development.
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