ArticleThe Biochemical journal1990
Immunological localization of ribosomes in striated rat muscle. Evidence for myofibrillar association and ontological changes in the subsarcolemmal:myofibrillar distribution.
Article in The Biochemical journal, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed, 55 citations in OpenAlex.
- Review
- The skeletal muscle fiber periphery: A nexus of mTOR-related anabolism.Sports medicine and health science · 2023Review
- More than just a garbage can: emerging roles of the lysosome as an anabolic organelle in skeletal muscle.American journal of physiology. Cell physiology · 2020Review
- The Importance of mTOR Trafficking for Human Skeletal Muscle Translational Control.Exercise and sport sciences reviews · 2019Review
- Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle.Scientific reports · 2017Article
- hsp70 mRNA temporal localization in rat skeletal myofibers and blood vessels post-exercise.Cell stress & chaperones · 2012Article
- Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling.The Journal of physiology · 2011Article
- In vivo monitoring of mRNA movement in Drosophila body wall muscle cells reveals the presence of myofiber domains.PloS one · 2009Article
- Sorting of beta-actin mRNA and protein to neurites and growth cones in culture.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1998Article
- Translocation of RNA granules in living neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1996Article
- Expression of fibronectin, laminin and ribosomes in normal and nocodazole-treated neonatal heart cells in culture: a study by laser scanning confocal microscopy and immunocytochemistry.Cell and tissue research · 1995Article
- Translation and the cytoskeleton: a mechanism for targeted protein synthesis.Molecular biology reports · 1994Review
- Alterations in glycosaminoglycan concentration and sulfation during chondrocyte maturation.Calcified tissue international · 1994Article
- Ultrastructural localization of myoglobin mRNA in human skeletal muscle.Histochemistry · 1994Article
- Ribosome distribution in normal and infarcted rat hearts.The Histochemical journal · 1994Article
- In situ hybridization of myoglobin mRNA: results on the skeletal muscles of normal subjects and patients with neuromuscular diseases.Acta neuropathologica · 1993Article
- Myosin heavy-chain mRNA is present in both myofibrillar and subsarcolemmal regions of muscle fibres.The Biochemical journal · 1991Article
- Interaction between mRNA, ribosomes and the cytoskeleton.The Biochemical journal · 1991Review
- Increased association of ribosomes with myofibrils during the skeletal-muscle hypertrophy induced either by the beta-adrenoceptor agonist clenbuterol or by tenotomy.The Biochemical journal · 1990Article
- In situ hybridization of slow myosin heavy chain mRNA in normal and transforming rabbit muscles with the use of a nonradioactively labeled cRNA.Histochemistry · 1990Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ribosome distribution in skeletal-muscle fibres was investigated immunohistochemically by using polyclonal antibodies raised against large-ribosomal-subunit proteins isolated from rat liver. Immunoblot analysis showed the antibodies to recognize five major proteins of the large subunit; these were identified as L4, L6, L7, L15 and L17 by two-dimensional electrophoresis. Immunohistochemistry of frozen rat skeletal-muscle sections showed staining of both the subsarcolemmal and intermyofibrillar cytoplasm. A distinct banding pattern was observed, and when peroxidase and phase-contrast images of the same field were compared by image analysis the anti-ribosome staining was found to correspond to the A-bands. These results suggest that a proportion of muscle ribosomes are present in the myofibrillar cytoplasm in a regular fashion, possibly associated with myosin. Densitometric analysis of the peroxidase immunostaining showed that the ratio of myofibrillar to sub-sarcolemmal ribosomal material was lower in muscle from 51-day-old rats compared with those from 14-day-old animals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.