ArticleCurrent genomics2011
Perspectives on Systematic Analyses of Gene Function in Arabidopsis thaliana: New Tools, Topics and Trends.
Article in Current genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Exogenous abscisic acid treatment regulates protein secretion in sorghum cell suspension cultures.Plant signaling & behavior · 2023Article
- The roles of plant proteases and protease inhibitors in drought response: a review.Frontiers in plant science · 2023Review
- Overexpression mutants reveal a role for a chloroplast MPD protein in regulation of reactive oxygen species during chilling in Arabidopsis.Journal of experimental botany · 2022Article
- Protocol for screening and expression studies of T-DNA and tagging-based insertional3 Biotech · 2021Article
- Rolling Circle Amplification (RCA)-Mediated Genome-Wide ihpRNAi Mutant Library Construction inInternational journal of molecular sciences · 2020Article
- Architecture and Dynamics of the Jasmonic Acid Gene Regulatory Network.The Plant cell · 2017Article
- Article
- Phenotypic screening with primary neurons to identify drug targets for regeneration and degeneration.Molecular and cellular neurosciences · 2017Review
- The Arabidopsis paralogs, PUB46 and PUB48, encoding U-box E3 ubiquitin ligases, are essential for plant response to drought stress.BMC plant biology · 2017Article
- Enhancing the GABI-Kat Arabidopsis thaliana T-DNA Insertion Mutant Database by Incorporating Araport11 Annotation.Plant & cell physiology · 2017Article
- Genomic and Phenomic Screens for Flower Related RING Type Ubiquitin E3 Ligases inFrontiers in plant science · 2017Article
- Genomics Approaches For Improving Salinity Stress Tolerance in Crop Plants.Current genomics · 2016Article
- Gain-of-function inSpringerPlus · 2016Article
- TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASE-Mediated Generation and Metabolic Analysis of Camalexin-Deficient cyp71a12 cyp71a13 Double Knockout Lines.Plant physiology · 2015Article
- Efficient isolation of ion beam-induced mutants for homoeologous loci in common wheat and comparison of the contributions of Glu-1 loci to gluten functionality.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2014Article
- The Arabidopsis Plant Intracellular Ras-group LRR (PIRL) Family and the Value of Reverse Genetic Analysis for Identifying Genes that Function in Gametophyte Development.Plants (Basel, Switzerland) · 2013Article
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- TILLING: a shortcut in functional genomics.Journal of applied genetics · 2011Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the sequencing of the nuclear genome of Arabidopsis thaliana ten years ago, various large-scale analyses of gene function have been performed in this model species. In particular, the availability of collections of lines harbouring random T-DNA or transposon insertions, which include mutants for almost all of the ~27,000 A. thaliana genes, has been crucial for the success of forward and reverse genetic approaches. In the foreseeable future, genome-wide phenotypic data from mutant analyses will become available for Arabidopsis, and will stimulate a flood of novel in-depth gene-function analyses. In this review, we consider the present status of resources and concepts for systematic studies of gene function in A. thaliana. Current perspectives on the utility of loss-of-function and gain-of-function mutants will be discussed in light of the genetic and functional redundancy of many A. thaliana genes.
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