Evidence map›Paper›PMID 21884640›Full record

ReviewBreast cancer research : BCR2011

Vitamin D and breast cancer: interpreting current evidence.

Rowan T Chlebowski

Open access · goldAbstract readReview
In one paragraph

Review in Breast cancer research : BCR, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Tumor Expression of Vitamin D Receptor and Breast Cancer Histopathological Characteristics and Prognosis.Clinical cancer research : an official journal of the American Association for Cancer Research · 2017
    Article
  5. Genetic variation in vitamin D-related genes and risk of breast cancer among women of European and East Asian descent.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  6. Article
  7. The association between Vitamin D and health outcomes in women: A review on the related evidence.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2016
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Cellular and molecular effects of vitamin D on carcinogenesis.Archives of biochemistry and biophysics · 2012
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Rowan T ChlebowskiLos Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 11243 West Carson Street, Torrance, CA 90502, USA. rowanchlebowski@gmail.com
Harbor–UCLA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preclinical investigations and selected clinical observational studies support an association between higher vitamin D intake and 25-hydroxyvitamin D levels with lower breast cancer risk. However, the recently updated report from the Institute of Medicine concluded that, for cancer and vitamin D, the evidence was 'inconsistent and insufficient to inform nutritional requirements'. Against this background, reports examining vitamin D intake, 25-hydroxyvitamin D levels and breast cancer incidence and outcome were reviewed. Current evidence supports the pursuit of several research questions but not routine 25-hydroxyvitamin D monitoring and vitamin D supplementation to reduce breast cancer incidence or improve breast cancer outcome.

Indexed as

ArthralgiaBreastBreast NeoplasmsCalciumDietary SupplementsFemaleHumansMammographyRadionuclide ImagingRandomized Controlled Trials as TopicVitamin D25-hydroxyvitamin DCalciumVitamin D

Identifiers

PMID21884640
PMCPMC3236325
OpenAlexW2125422139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.