Evidence map›Paper›PMID 21884130›Full record

ReviewNutrition reviews2011

Balancing the benefits of n-3 polyunsaturated fatty acids and the risks of methylmercury exposure from fish consumption.

Kathryn R Mahaffey, Elsie M Sunderland, Hing Man Chan, Anna L Choi, Philippe Grandjean, Koenraad Mariën, Emily Oken, Mineshi Sakamoto, Rita Schoeny, Pál Weihe and 2 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Nutrition reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 1 pooled it
17.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 1 synthesis or guideline pooled it, 249 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Global fishing patterns amplify human exposures to methylmercury.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Mercury isotopic evidence for the importance of particles as a source of mercury to marine organisms.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Kathryn R MahaffeyDepartment of Occupational and Environmental Health, George Washington University School of Public Health, Washington DC, USA.
Elsie M Sunderland
Hing Man Chan
Anna L Choi
Philippe Grandjean
Koenraad Mariën
Emily Oken
Mineshi Sakamoto
Rita Schoeny
Pál Weihe
Chong-Huai Yan
Akira Yasutake
Center for Environmental Health · USGeorge Washington University · US

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTOPHER P DUGGAN · 1994 to 2026
$31.6M
NIDDK NIH HHS P30 DK040561
6 · The paper itself

Abstract

Fish and shellfish are widely available foods that provide important nutrients, particularly n-3 polyunsaturated fatty acids (n-3 PUFAs), to many populations globally. These nutrients, especially docosahexaenoic acid, confer benefits to brain and visual system development in infants and reduce risks of certain forms of heart disease in adults. However, fish and shellfish can also be a major source of methylmercury (MeHg), a known neurotoxicant that is particularly harmful to fetal brain development. This review documents the latest knowledge on the risks and benefits of seafood consumption for perinatal development of infants. It is possible to choose fish species that are both high in n-3 PUFAs and low in MeHg. A framework for providing dietary advice for women of childbearing age on how to maximize the dietary intake of n-3 PUFAs while minimizing MeHg exposures is suggested.

Indexed as

Food ContaminationAdultChildChild DevelopmentDietFatty Acids, Omega-3FemaleHealth PromotionHumansInfantMaleMaternal ExposureMethylmercury CompoundsNeurotoxicity SyndromesRisk AssessmentSeafoodFatty Acids, Omega-3Methylmercury CompoundsWater Pollutants, Chemical

Identifiers

PMID21884130
PMCPMC3219437
OpenAlexW2110086012

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.