Evidence map›Paper›PMID 21883109›Full record

Trial reportJournal of the American Geriatrics Society2011

Meaningful improvement in gait speed in hip fracture recovery.

Dawn E Alley, Gregory E Hicks, Michelle Shardell, William Hawkes, Ram Miller, Rebecca L Craik, Kathleen K Mangione, Denise Orwig, Marc Hochberg, Barbara Resnick and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Geriatrics Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Creatine monohydrate supplementation for older adults and clinical populations.Journal of the International Society of Sports Nutrition · 2025
    Review
  9. Thigh Muscle Composition and Its Relationship to Functional Recovery Post Hip Fracture Over Time and Between Sexes.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Application of SDOC Cut Points for Low Muscle Strength for Recovery of Walking Speed After Hip Fracture.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Gait Performance in Hypertensive Patients on Angiotensin-Converting Enzyme Inhibitors.Journal of the American Medical Directors Association · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dawn E AlleyDepartments of Epidemiology and Public Health, School of Medicine, University of Maryland, Baltimore, Maryland, USA. dalley@epi.umaryland.edu
Gregory E Hicks
Michelle Shardell
William Hawkes
Ram Miller
Rebecca L Craik
Kathleen K Mangione
Denise Orwig
Marc Hochberg
Barbara Resnick
Jay Magaziner

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Sequelae of Hip Fracture in Men: An Epidemiologic StudyR37AG009901 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 1992 to 2018
$11.3M
Maryland's Organized Research Effort in Women's Health (MORE-WH)K12HD043489 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI TRACY, J. KATHLEEN · 2002 to 2016
$7.0M
Determinants of Recovery Following Hip FractureR01AG018668 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY STEVEN · 2001 to 2004
$2.3M
TESTING THE EXERCISE PLUS PROGRAM FOLLOWING HIP FRACTURER01AG017082 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI RESNICK, BARBARA M · 1999 to 2002
$1.6M
Consequences of Inflammation on Muscle Following Hip FractureK23AG027746 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MILLER, RAM R · 2008 to 2011
$646k
Statistical Methods to Correct for Proxy Bias in Studies of Older AdultsK25AG034216 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI SHARDELL, MICHELLE DENISE · 2011 to 2013
$401k
DETERMINANTS OF RECOVERY FROM HIP FX/SUP BONE/MUSCLER55AG009901 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY STEVEN · 1991 to 1991
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NIA NIH HHS K23 AG027746NIA NIH HHS K23AG027746NIA NIH HHS K25AG03421NIA NIH HHS K25 AG034216NIA NIH HHS P30 AG028747NIA NIH HHS P30AG028747NIA NIH HHS R01 AG017082NIA NIH HHS R01 AG018668NIA NIH HHS R01AG17082NIA NIH HHS R01AG18668NIA NIH HHS R37 AG009901NIA NIH HHS R37AG09901NICHD NIH HHS K12 HD043489NICHD NIH HHS K12HD043489
6 · The paper itself

Abstract

objectivesTo estimate meaningful improvements in gait speed observed during recovery from hip fracture and to evaluate the sensitivity and specificity of gait speed changes in detecting change in self-reported mobility.

designSecondary longitudinal data analysis from two randomized controlled trials

settingTwelve hospitals in the Baltimore, Maryland, area.

participantsTwo hundred seventeen women admitted with hip fracture. MEASUREMENTS: Usual gait speed and self-reported mobility (ability to walk 1 block and climb 1 flight of stairs) measured 2 and 12 months after fracture.

resultsEffect size-based estimates of meaningful differences were 0.03 for small differences and 0.09 for substantial differences. Depending on the anchor (stairs vs walking) and method (mean difference vs regression), anchor-based estimates ranged from 0.10 to 0.17 m/s for small meaningful improvements and 0.17 to 0.26 m/s for substantial meaningful improvement. Optimal gait speed cutpoints yielded low sensitivity (0.39-0.62) and specificity (0.57-0.76) for improvements in self-reported mobility.

conclusionResults from this sample of women recovering from hip fracture provide only limited support for the 0.10-m/s cut point for substantial meaningful change previously identified in community-dwelling older adults experiencing declines in walking abilities. Anchor-based estimates and cut points derived from receiver operating characteristic curve analysis suggest that greater improvements in gait speed may be required for substantial perceived mobility improvement in female hip fracture patients. Furthermore, gait speed change performed poorly in discriminating change in self-reported mobility. Estimates of meaningful change in gait speed may differ based on the direction of change (improvement vs decline) or between patient populations.

Indexed as

GaitWalkingAgedAged, 80 and overFemaleHip FracturesHumansRecovery of Function

Identifiers

PMID21883109
PMCPMC3230716

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.