ArticleJournal of molecular neuroscience : MN2011
Behavioral variant frontotemporal dementia with corticobasal degeneration pathology: phenotypic comparison to bvFTD with Pick's disease.
Article in Journal of molecular neuroscience : MN, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Patterns of gray matter atrophy in atypical parkinsonism syndromes: a VBM meta-analysis.Brain and behavior · 2015Pooled it
- Transcranial Magnetic Stimulation in Parkinson's Disease and Parkinsonian Syndromes: A Narrative Expert Review.Life (Basel, Switzerland) · 2026Review
- Shared Neuroinflammatory Mechanisms Across Dementia Types: An Integrative Review.International journal of molecular sciences · 2025Review
- Apraxia phenotypes and frontotemporal lobar degeneration.Journal of neurology · 2024Article
- Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias.Acta neuropathologica communications · 2024Article
- Clinical, neuroimaging, and neuropathological characterization of a patient with Alzheimer's disease syndrome due to Pick's pathology.Neurocase · 2022Article
- Neuroimaging in Frontotemporal Dementia: Heterogeneity and Relationships with Underlying Neuropathology.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021Review
- Longitudinal anatomic, functional, and molecular characterization of Pick disease phenotypes.Neurology · 2020Article
- Tauopathies: Deciphering Disease Mechanisms to Develop Effective Therapies.International journal of molecular sciences · 2020Review
- Pick's disease: clinicopathologic characterization of 21 cases.Journal of neurology · 2020Article
- Exploration Deficits Under Ecological Conditions as a Marker of Apathy in Frontotemporal Dementia.Frontiers in neurology · 2019Article
- FTD spectrum: Neuroimaging across the FTD spectrum.Progress in molecular biology and translational science · 2019Review
- Neuroimaging in Dementia.Seminars in neurology · 2017Review
- A clinicopathological approach to the diagnosis of dementia.Nature reviews. Neurology · 2017Review
- Prognosis of Patients with Behavioral Variant Frontotemporal Dementia Who have Focal Versus Diffuse Frontal Atrophy.Journal of clinical neurology (Seoul, Korea) · 2017Article
- Frontotemporal Dementia.Neurologic clinics · 2017Review
- The association of aphasia and right-sided motor impairment in corticobasal syndrome.Journal of neurology · 2015Article
- Biomarkers in dementia: clinical utility and new directions.Journal of neurology, neurosurgery, and psychiatry · 2014Review
- Diagnosis and management of behavioral variant frontotemporal dementia.Biological psychiatry · 2014Review
- Frontotemporal dementia: diagnosis, deficits and management.Neurodegenerative disease management · 2014Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Patients with corticobasal degeneration (CBD) pathology present with diverse clinical syndromes also associated with other neuropathologies, including corticobasal syndrome, progressive nonfluent aphasia, and an Alzheimer's-type dementia. Some present with behavioral variant frontotemporal dementia (bvFTD), though this subtype still requires more detailed clinical characterization. All patients with CBD pathology and clinical assessment were reviewed (N = 17) and selected if they initially met criteria for bvFTD [bvFTD(CBD), N = 5]. Available bvFTD patients with Pick's [bvFTD(Pick's), N = 5] were selected as controls. Patients were also compared to healthy older controls [N = 53] on neuropsychological and neuroimaging measures. At initial presentation, bvFTD(CBD) showed few neuropsychological or motor differences from bvFTD(Pick's). Neuropsychiatrically, they were predominantly apathetic with less florid social disinhibition and eating disturbances, and were more anxious than bvFTD(Pick's) patients. Voxel-based morphometry revealed similar patterns of predominantly frontal atrophy between bvFTD groups, though overall degree of atrophy was less severe in bvFTD(CBD), who also showed comparative preservation of the frontoinsular rim, with dorsal > ventral frontal atrophy, and sparing of temporal and parietal structures relative to bvFTD(Pick's) patients. Despite a remarkable overlap between the two patient types, bvFTD patients with underlying CBD pathology show subtle clinical features that may distinguish them from patients with Pick's disease neuropathology.
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