ArticleThe ISME journal2012
Sustainable syntrophic growth of Dehalococcoides ethenogenes strain 195 with Desulfovibrio vulgaris Hildenborough and Methanobacterium congolense: global transcriptomic and proteomic analyses.
Article in The ISME journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed, 159 citations in OpenAlex.
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- Competitive Inhibition and Pathway Truncation During Biotransformation of Traditional and Novel Brominated Flame Retardants Using a Dehalogenimonas-Rich Consortium: Chemical and Microbiological Insights.International journal of molecular sciences · 2026Article
- The Effects of Biochar on the Revival and Performance of an Organohalide-Respiring Mixed Culture.Environmental science & technology · 2026Article
- Biotransformation and biodefluorination of chlorinated polyfluorocarboxylic acids bybioRxiv : the preprint server for biology · 2026Article
- Mono-mix strategy enables comparative proteomics of a cross-kingdom microbial symbiosis.PloS one · 2026Article
- Complete metagenome-assembled genome sequence ofMicrobiology resource announcements · 2025Article
- Bibliometrics and Visualization Analysis of Three Obligate Organohalide Respiring Bacteria Genera: A Systematic Review.Microorganisms · 2025Review
- Developing a microbial community structure index (MCSI) as an approach to evaluate and optimize bioremediation performance.Biodegradation · 2024Article
- Burning question: Rethinking organohalide degradation strategy for bioremediation applications.Microbial biotechnology · 2024Review
- Synergistic material-microbe interface toward deeper anaerobic defluorination.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Metabolite cross-feeding enables concomitant catabolism of chlorinated methanes and chlorinated ethenes in synthetic microbial assemblies.The ISME journal · 2024Article
- Understanding the sources, function, and irreplaceable role of cobamides in organohalide-respiring bacteria.Frontiers in microbiology · 2024Review
- Syntrophic Interactions Ameliorate Arsenic Inhibition of Solvent-DechlorinatingEnvironmental science & technology · 2023Article
- Thiamine-Mediated Microbial Interaction between Auxotrophic Rhodococcus ruber ZM07 and Prototrophic Cooperators in the Tetrahydrofuran-Degrading Microbial Community H-1.Microbiology spectrum · 2023Article
- Substantial defluorination of polychlorofluorocarboxylic acids triggered by anaerobic microbial hydrolytic dechlorination.Nature water · 2023Article
- Effect of wine pomace extract on dechlorination of chloroethenes in soil suspension.Bioresources and bioprocessing · 2023Article
- mibPOPdb: An online database for microbial biodegradation of persistent organic pollutants.iMeta · 2022Article
- Combined read- and assembly-based metagenomics to reconstruct a Dehalococcoides mccartyi genome from PCB-contaminated sediments and evaluate functional differences among organohalide-respiring consortia in the presence of different halogenated contaminants.FEMS microbiology ecology · 2022Article
- Dehalogenation of Chlorinated Ethenes to Ethene by a Novel Isolate, "Applied and environmental microbiology · 2022Article
- 'Cry-for-help' in contaminated soil: a dialogue among plants and soil microbiome to survive in hostile conditions.Environmental microbiology · 2021Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 3 countries.
Funding
Abstract
Dehalococcoides ethenogenes strain 195 (DE195) was grown in a sustainable syntrophic association with Desulfovibrio vulgaris Hildenborough (DVH) as a co-culture, as well as with DVH and the hydrogenotrophic methanogen Methanobacterium congolense (MC) as a tri-culture using lactate as the sole energy and carbon source. In the co- and tri-cultures, maximum dechlorination rates of DE195 were enhanced by approximately three times (11.0±0.01 μmol per day for the co-culture and 10.1±0.3 μmol per day for the tri-culture) compared with DE195 grown alone (3.8±0.1 μmol per day). Cell yield of DE195 was enhanced in the co-culture (9.0±0.5 × 10(7) cells per μmol Cl(-) released, compared with 6.8±0.9 × 10(7) cells per μmol Cl(-) released for the pure culture), whereas no further enhancement was observed in the tri-culture (7.3±1.8 × 10(7) cells per μmol Cl(-) released). The transcriptome of DE195 grown in the co-culture was analyzed using a whole-genome microarray targeting DE195, which detected 102 significantly up- or down-regulated genes compared with DE195 grown in isolation, whereas no significant transcriptomic difference was observed between co- and tri-cultures. Proteomic analysis showed that 120 proteins were differentially expressed in the co-culture compared with DE195 grown in isolation. Physiological, transcriptomic and proteomic results indicate that the robust growth of DE195 in co- and tri-cultures is because of the advantages associated with the capabilities of DVH to ferment lactate to provide H(2) and acetate for growth, along with potential benefits from proton translocation, cobalamin-salvaging and amino acid biosynthesis, whereas MC in the tri-culture provided no significant additional benefits beyond those of DVH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.