Evidence map›Paper›PMID 21880861›Full record

ReviewThe oncologist2011

Symptom management in metastatic breast cancer.

William Irvin, Hyman B Muss, Deborah K Mayer

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in The oncologist, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02186015 (Safety, Feasibility and Efficacy of Vitamin D Supplementation in Women With Metastatic Breast Cancer), which is not on this map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02186015 phase2completednot on this mapstarted 2015, after this paper: background citation

Safety, Feasibility and Efficacy of Vitamin D Supplementation in Women With Metastatic Breast Cancer (SAFE-D)

TypeinterventionalSponsorLoyola UniversityRan2015 to 2017Enrolled43ConditionsAdult Women, Metastatic Breast Cancer, Estrogen Receptor PositiveArmsCholecalciferol
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 108 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Feasibility of a mindful yoga program for women with metastatic breast cancer: results of a randomized pilot study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Trial
  4. Trial
  5. Trial
  6. Functional benefits are sustained after a program of supervised resistance exercise in cancer patients with bone metastases: longitudinal results of a pilot study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2014
    Trial
  7. Article
  8. Exploring the lived experiences of women with metastatic breast cancer and their HRQoL questionnaire preferences: a qualitative study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Review
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  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

William IrvinR.N., A.O.C.N., F.A.A.N., School of Nursing, Carrington Hall #7460, UNC-Chapel Hill, Chapel Hill, North Carolina 27599-7460, USA.
Hyman B Muss
Deborah K Mayer
University of North Carolina at Chapel Hill · USUNC Lineberger Comprehensive Cancer Center

Funding

Tissue Procurement & PathologyP50CA058223 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KATHERINE A. HOADLEY · 1992 to 2026
$59.3M
NCI NIH HHS P50 CA058223
6 · The paper itself

Abstract

Approximately 40,000 women die as a result of breast cancer each year and many more live with advanced disease. When breast cancer recurs, the goals of treatment often shift from one of cure to controlling the disease for as long as possible while palliating symptoms interfering with the patient's functional status and quality of life. This requires ongoing discussions with the patient and family about the goals of care. Many symptoms depend on the site of metastasis, with bone being the most frequent, and commonly occur with fatigue, depression, insomnia, and pain. The purpose of this paper is to identify and provide an overview of the management of the most common symptoms in patients with breast cancer metastases.

Indexed as

Breast NeoplasmsFemaleHumansNeoplasm MetastasisPalliative CareQuality of Life

Identifiers

PMID21880861
PMCPMC3228166
OpenAlexW2124234139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.