ArticleThe American journal of clinical nutrition2011
Association of dietary sodium and potassium intakes with albuminuria in normal-weight, overweight, and obese participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study.
Article in The American journal of clinical nutrition, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 36 citations in OpenAlex.
- Association of Urinary Sodium, Potassium, and the Sodium-to-Potassium Ratio with Impaired Kidney Function Assessed with 24-H Urine Analysis.Nutrients · 2024Article
- Self-Reported Frequency of Adding Salt to Food and Risk of Incident Chronic Kidney Disease.JAMA network open · 2023Article
- Being overweight worsens the relationship between urinary sodium excretion and albuminuria: the Wakuya study.European journal of clinical nutrition · 2023Article
- Association of 24-h urinary sodium excretion with microalbuminuria in a Chinese population.Scientific reports · 2023Article
- Associations of sodium and potassium intake with chronic kidney disease in a prospective cohort study: findings from the Hispanic Community Health Study/Study of Latinos, 2008-2017.BMC nephrology · 2022Article
- Identifying Distinct Risk Thresholds of Glycated Hemoglobin and Systolic Blood Pressure for Rapid Albuminuria Progression in Type 2 Diabetes From NHANES (1999-2018).Frontiers in medicine · 2022Article
- Identifying Excessive Intake of Oil and Salt to Prevent and Control Hypertension: A Latent Class Analysis.Frontiers in cardiovascular medicine · 2022Article
- Association of Sodium, Potassium and Sodium-to-Potassium Ratio with Urine Albumin Excretion among the General Chinese Population.Nutrients · 2021Article
- Plant food intake is associated with lower cadmium body burden in middle-aged adults.European journal of nutrition · 2021Article
- Magnesium intake is inversely associated with the risk of metabolic syndrome in the REasons for geographic and racial differences in stroke (REGARDS) cohort study.Clinical nutrition (Edinburgh, Scotland) · 2021Article
- Article
- Association of Urinary Sodium Excretion and Diabetic Kidney Disease in Patients With Type 2 Diabetes Mellitus: A Cross-Sectional Study.Frontiers in endocrinology · 2021Article
- Genome-wide association study identifies new loci for albuminuria in the Japanese population.Clinical and experimental nephrology · 2020Article
- Results of the CARDIA study suggest that higher dietary potassium may be kidney protective.Kidney international · 2020Article
- Calcium Intake and Serum Calcium Level in Relation to the Risk of Ischemic Stroke: Findings from the REGARDS Study.Journal of stroke · 2019Article
- Salt-induced effects on microvascular function: A critical factor in hypertension mediated organ damage.Journal of clinical hypertension (Greenwich, Conn.) · 2019Review
- Serum mercury concentration and the risk of ischemic stroke: The REasons for Geographic and Racial Differences in Stroke Trace Element Study.Environment international · 2018Article
- Urinary cadmium concentration and the risk of ischemic stroke.Neurology · 2018Article
- Dietary Sodium to Potassium Ratio and the Incidence of Chronic Kidney Disease in Adults: A Longitudinal Follow-Up Study.Preventive nutrition and food science · 2018Article
- The relationship between sodium excretion and blood pressure, urine albumin, central retinal arteriolar equivalent.BMC cardiovascular disorders · 2016Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAmong obese adults, sodium intake has been associated with cardiovascular disease. Few data are available on sodium intake and albuminuria, a marker of kidney damage and risk factor for cardiovascular disease.
objectiveWe examined the relation between dietary sodium and potassium intakes and the ratio of sodium to potassium (Na/K) with albuminuria by BMI in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study (n = 30,239 adults aged ≥45 y).
designA modified Block 98 food-frequency questionnaire was used for dietary assessment in 21,636 participants, and nutritional variables were categorized by sex-specific quintiles. Normal weight, overweight, and obese were defined as BMI (in kg/m(2)) categories of 18.5-24.9, 25-29.9, and ≥30, respectively. Albuminuria was defined as a ratio (mg/g) of urinary albumin to creatinine of ≥30.
resultsThe prevalences of albuminuria were 11.5%, 11.6%, and 16.0% in normal-weight, overweight, and obese participants, respectively. The multivariable-adjusted ORs for albuminuria in a comparison of the highest with the lowest quintile of Na/K intake (≥1.12 to <0.70 for men and ≥1.07 to <0.62 for women) were 0.89 (95% CI: 0.65, 1.22), 1.08 (95% CI: 0.85, 1.36), and 1.28 (95% CI: 1.02, 1.61) in normal-weight, overweight, and obese participants, respectively. The highest quintile of dietary sodium was associated with an increased OR for albuminuria in obese participants (OR: 1.44; 95% CI: 1.00, 2.07) but not in normal-weight or overweight participants. Dietary potassium was not associated with albuminuria.
conclusionIn obese adults, higher dietary Na/K and sodium intakes were associated with albuminuria.
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