ArticleThe Journal of clinical endocrinology and metabolism2011
Associations of salivary cortisol levels with metabolic syndrome and its components: the multi-ethnic study of atherosclerosis.
Article in The Journal of clinical endocrinology and metabolism, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Effect of restorative yoga vs. stretching on diurnal cortisol dynamics and psychosocial outcomes in individuals with the metabolic syndrome: the PRYSMS randomized controlled trial.Psychoneuroendocrinology · 2014Trial
- Resistance training increases SHBG in overweight/obese, young men.Metabolism: clinical and experimental · 2013Trial
- Molecular Pathways of Endothelial Dysfunction Induced by Chronic Social Stress and Therapeutic Interventions.Journal of cardiovascular translational research · 2025Review
- Night Shift Work and Poor Sleep Quality Among Female Workers in Southern Brazil: A Repeated Cross-Sectional Study (2017-2022).Nature and science of sleep · 2025Article
- Behavioural characteristics and abdominal obesity among Brazilian shift working women.Public health nutrition · 2021Article
- Perceived stress, psychological resilience, hair cortisol concentration, and metabolic syndrome severity: A moderated mediation model.Psychoneuroendocrinology · 2020Article
- Role of Mineralocorticoid Receptor in Adipogenesis and Obesity in Male Mice.Endocrinology · 2020Article
- SALIVARY CORTISOL AND METABOLIC SYNDROME COMPONENT'S ASSOCIATION.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2018Article
- Association of psychosocial stressors with metabolic syndrome severity among African Americans in the Jackson Heart Study.Psychoneuroendocrinology · 2018Article
- Cortisol dysregulation: the bidirectional link between stress, depression, and type 2 diabetes mellitus.Annals of the New York Academy of Sciences · 2017Review
- Antecedent longitudinal changes in body mass index are associated with diurnal cortisol curve features: The multi-ethnic study of atherosclerosis.Metabolism: clinical and experimental · 2017Article
- Diurnal salivary cortisol, glycemia and insulin resistance: The multi-ethnic study of atherosclerosis.Psychoneuroendocrinology · 2015Article
- The Association between Midnight Salivary Cortisol and Metabolic Syndrome in Korean Adults.Diabetes & metabolism journal · 2012Article
- The role of cortisol in the pathogenesis of the metabolic syndrome.Diabetes & metabolism journal · 2012Article
- High-protein meal challenge reveals the association between the salivary cortisol response and metabolic syndrome in police officers.American journal of human biology : the official journal of the Human Biology CouncilArticle
- Depressive symptoms, psychiatric medication use, and risk of type 2 diabetes: results from the Health and Retirement Study.General hospital psychiatryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
contextPrior research has identified associations between social-environmental factors and metabolic syndrome (MetS) components. The physiological mechanisms underlying these associations are not fully understood, but alterations in activity of the hypothalamic-pituitary-adrenal axis, a stress-responsive biological system, have been hypothesized to play a role.
objectiveThe aim of the study was to determine whether MetS diagnosis and specific clusters of MetS components (waist circumference, high-density lipoproteins, glucose, and blood pressure) are associated with cortisol levels. DESIGN AND
settingWe conducted cross-sectional analyses of data from the Multi-Ethnic Study of Atherosclerosis (MESA) study in the general community. PATIENTS OR OTHER
participantsWe studied a population-based sample of 726 adults (ages 48 to 89 yr) who do not have clinical diabetes. INTERVENTION(S): There were no interventions. MAIN OUTCOME MEASURE(S): Cortisol awakening response, cortisol decline across the waking day, and total cortisol output were analyzed (using 18 timed measures of salivary cortisol over 3 d).
resultsOverall, we found little evidence that the presence of MetS or its components is related to cortisol output or patterns. Contrary to expectation, the presence of MetS was associated with lower rather than higher area under the curve, and no consistent pattern was observed when MetS components or subsets of components were examined in relation to cortisol.
conclusionsOur findings do not support the hypothesis that differences in level or diurnal pattern of salivary cortisol output are associated with MetS among persons without clinical diabetes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.