Evidence map›Paper›PMID 21879342›Full record

ArticleVirus genes2012

Determination of the full length sequence of a chicken astrovirus suggests a different replication mechanism.

Kyung-il Kang, Alan H Icard, Erich Linnemann, Holly S Sellers, Egbert Mundt

Abstract read
PubMed Publisher
In one paragraph

Article in Virus genes, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Screening and identification of protein interacting with goose astrovirus.Frontiers in cellular and infection microbiology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Human astroviruses.Clinical microbiology reviews · 2014
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kyung-il KangPoultry Diagnostic and Research Center, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Alan H Icard
Erich Linnemann
Holly S Sellers
Egbert Mundt
University of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genomic RNA of a novel chicken astrovirus was determined. The full length sequence is 7520 nucleotides and encodes three open reading frames (1a, 1b, 2) for three proteins. The genomic organization was similar to other astroviruses with two exceptions. The open reading frame of the RNA-dependent RNA polymerase contains its own start codon which is different from other astroviruses described to date, providing evidence for a replication mechanism different than what has previously been described for astroviruses. Furthermore, the stem-loop structure located at the potential ribosomal frameshift signal described for other astroviruses has been shown to be a hairpin structure for the novel chicken astrovirus. Phylogenic analysis of the full length sequence revealed that this chicken astrovirus formed a branch independent from other astroviruses, indicating that this astrovirus is significantly different from astroviruses described to date.

Indexed as

Genome, ViralVirus ReplicationAmino Acid SequenceAnimalsAstroviridae InfectionsAvastrovirusBase SequenceChickensMolecular Sequence DataPhylogenyPoultry DiseasesRNA-Dependent RNA PolymeraseViral ProteinsRNA-Dependent RNA PolymeraseViral Proteins

Identifiers

PMID21879342
OpenAlexW1972284642

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.