ArticleProceedings of the National Academy of Sciences of the United States of America2011
Horizontal gene transfer facilitated the evolution of plant parasitic mechanisms in the oomycetes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers.
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Who cites it
117 citing papers in PubMed, 253 citations in OpenAlex.
- Reversal to osmotrophy in eukaryotes.Nature ecology & evolution · 2026Article
- Signatures of gene transfer in the parallel evolution of osmotrophic specialization in eukaryotes.Nature ecology & evolution · 2026Article
- Endophytic entomopathogenic fungi: The next frontier in mycological biocontrol.World journal of microbiology & biotechnology · 2026Review
- Harnessing endophytes and Multi-Omics for sustainable Colchicine biosynthesis.World journal of microbiology & biotechnology · 2026Review
- Cross-Kingdom Enzymatic Strategies for Deoxynivalenol Detoxification: Computational Analysis of Structural Mechanisms and Evolutionary Adaptations.Microorganisms · 2025Article
- Genome-Wide Analysis of Oxidosqualene Cyclase Genes inCurrent issues in molecular biology · 2025Article
- Specific selection on XEG1 and XLP1 genes correlates with host range and adaptability in Phytophthora.Nature communications · 2025Article
- Gene acquisition by giant transposons primes eukaryotes for rapid evolution via horizontal gene transfer.Science advances · 2024Article
- Horizontal transfers between fungal Fusarium species contributed to successive outbreaks of coffee wilt disease.PLoS biology · 2024Article
- Synthesis and biological evaluation of MS-347a derivatives against plant pathogenic fungi based on a strategy ofJournal of pesticide science · 2024Article
- Reconstructing the last common ancestor of all eukaryotes.PLoS biology · 2024Review
- Duplication and neofunctionalization of a horizontally transferred xyloglucanase as a facet of the Red Queen coevolutionary dynamic.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Horizontal gene transfer in eukaryotes: aligning theory with data.Nature reviews. Genetics · 2024Review
- Integrated overview of stramenopile ecology, taxonomy, and heterotrophic origin.The ISME journal · 2024Review
- What we know so far and what we can expect next: A molecular investigation of plant parasitism.Genetics and molecular biology · 2024Article
- Phyllosphere bacterial community dynamics in response to bacterial wildfire disease: succession and interaction patterns.Frontiers in plant science · 2024Article
- Eukaryotic CD-NTase, STING, and viperin proteins evolved via domain shuffling, horizontal transfer, and ancient inheritance from prokaryotes.PLoS biology · 2023Article
- Duplication and neofunctionalization of a horizontally-transferred xyloglucanase as a facet of the red queen co-evolutionary dynamic.bioRxiv : the preprint server for biology · 2023Article
- Horizontally Transferred DNA in the Genome of the Fungus Pyricularia oryzae is Associated With Repressive Histone Modifications.Molecular biology and evolution · 2023Article
- Eukaryotic antiviral immune proteins arose via convergence, horizontal transfer, and ancient inheritance.bioRxiv : the preprint server for biology · 2023Article
57 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Horizontal gene transfer (HGT) can radically alter the genomes of microorganisms, providing the capacity to adapt to new lifestyles, environments, and hosts. However, the extent of HGT between eukaryotes is unclear. Using whole-genome, gene-by-gene phylogenetic analysis we demonstrate an extensive pattern of cross-kingdom HGT between fungi and oomycetes. Comparative genomics, including the de novo genome sequence of Hyphochytrium catenoides, a free-living sister of the oomycetes, shows that these transfers largely converge within the radiation of oomycetes that colonize plant tissues. The repertoire of HGTs includes a large number of putatively secreted proteins; for example, 7.6% of the secreted proteome of the sudden oak death parasite Phytophthora ramorum has been acquired from fungi by HGT. Transfers include gene products with the capacity to break down plant cell walls and acquire sugars, nucleic acids, nitrogen, and phosphate sources from the environment. Predicted HGTs also include proteins implicated in resisting plant defense mechanisms and effector proteins for attacking plant cells. These data are consistent with the hypothesis that some oomycetes became successful plant parasites by multiple acquisitions of genes from fungi.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.