ReviewEnvironmental health perspectives2012
European birth cohorts for environmental health research.
Review in Environmental health perspectives, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Six decades of longitudinal health knowledge production: a systematic review on Nordic birth cohort studies.International journal of circumpolar health · 2023Pooled it
- Exposure to nitrogen dioxide and chronic obstructive pulmonary disease (COPD) in adults: a systematic review and meta-analysis.Environmental science and pollution research international · 2018Pooled it
- Occupational Exposure to Endocrine-Disrupting Chemicals and Birth Weight and Length of Gestation: A European Meta-Analysis.Environmental health perspectives · 2016Pooled it
- Global early-life cohorts for nutrition-neurodevelopment research including over 100 datasets representing over one million children.iScience · 2026Article
- Cohort Profile: The European Occupational Exposome Mega Cohort Consortium (OMega-X).International journal of epidemiology · 2026Article
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- Article
- Wearable Sensor-Based Monitoring of Environmental Exposures and the Associated Health Effects: A Review.Biosensors · 2022Review
- What is next for occupational cancer epidemiology?Scandinavian journal of work, environment & health · 2022Article
- REPRO_PL-Polish Mother and Child Cohort-Exposure, Health Status, and Neurobehavioral Assessments in Adolescents-Design and Cohort Update.International journal of environmental research and public health · 2022Article
- Mechanisms and biomarkers of successful allergen-specific immunotherapy.Asia Pacific allergy · 2022Review
- European birth cohorts: a consideration of what they have addressed so far.BMC pediatrics · 2022Article
- Gene-environment interactions related to maternal exposure to environmental and lifestyle-related chemicals during pregnancy and the resulting adverse fetal growth: a review.Environmental health and preventive medicine · 2022Review
- HBM4EU combines and harmonises human biomonitoring data across the EU, building on existing capacity - The HBM4EU survey.International journal of hygiene and environmental health · 2021Article
- Intrauterine Exposures and Maternal Health Status during Pregnancy in Relation to Later Child Health: A Review of Pregnancy Cohort Studies in Europe.International journal of environmental research and public health · 2021Review
- Hokkaido birth cohort study on environment and children's health: cohort profile 2021.Environmental health and preventive medicine · 2021Article
- Cohort Profile: Research Advancement through Cohort Cataloguing and Harmonization (ReACH).International journal of epidemiology · 2021Article
- The EU Child Cohort Network's core data: establishing a set of findable, accessible, interoperable and re-usable (FAIR) variables.European journal of epidemiology · 2021Article
- The Neonatal Environment and Health Outcomes (NEHO) Birth Cohort Study: Behavioral and Socioeconomic Characteristics and Drop-Out Rate from a Longitudinal Birth Cohort in Three Industrially Contaminated Sites in Southern Italy.International journal of environmental research and public health · 2021Article
- Next Generation Reproductive and Developmental Toxicology: Crosstalk Into the Future.Frontiers in toxicology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
40 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany pregnancy and birth cohort studies investigate the health effects of early-life environmental contaminant exposure. An overview of existing studies and their data is needed to improve collaboration, harmonization, and future project planning.
objectivesOur goal was to create a comprehensive overview of European birth cohorts with environmental exposure data.
methodsBirth cohort studies were included if they a) collected data on at least one environmental exposure, b) started enrollment during pregnancy or at birth, c) included at least one follow-up point after birth, d) included at least 200 mother-child pairs, and e) were based in a European country. A questionnaire collected information on basic protocol details and exposure and health outcome assessments, including specific contaminants, methods and samples, timing, and number of subjects. A full inventory can be searched on www.birthcohortsenrieco.net.
resultsQuestionnaires were completed by 37 cohort studies of > 350,000 mother-child pairs in 19 European countries. Only three cohorts did not participate. All cohorts collected biological specimens of children or parents. Many cohorts collected information on passive smoking (n = 36), maternal occupation (n = 33), outdoor air pollution (n = 27), and allergens/biological organisms (n = 27). Fewer cohorts (n = 12-19) collected information on water contamination, ionizing or nonionizing radiation exposures, noise, metals, persistent organic pollutants, or other pollutants. All cohorts have information on birth outcomes; nearly all on asthma, allergies, childhood growth and obesity; and 26 collected information on child neurodevelopment.
conclusionCombining forces in this field will yield more efficient and conclusive studies and ultimately improve causal inference. This impressive resource of existing birth cohort data could form the basis for longer-term and worldwide coordination of research on environment and child health.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.