ReviewNeural plasticity2011
Genetics and function of neocortical GABAergic interneurons in neurodevelopmental disorders.
Review in Neural plasticity, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
100 citing papers in PubMed, 193 citations in OpenAlex.
- Growth hormone-releasing hormone effects on brain γ-aminobutyric acid levels in mild cognitive impairment and healthy aging.JAMA neurology · 2013Trial
- Repeated Stress Escalates Aggression and Activity in Fronto-Limbic Regions in Cntnap2Genes, brain, and behavior · 2026Article
- Astrocytic GABA controls fidelity of temporal cortical processing in Fragile X Syndrome.Neurobiology of disease · 2026Article
- Functional KCC2 expression marks an evolutionarily conserved population of early-maturing interneurons in the perinatal cortex.Nature communications · 2025Article
- GABAergic signaling by VIP interneurons gates running-dependent visual recovery in the adult brain.bioRxiv : the preprint server for biology · 2025Article
- Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneurons.Molecular psychiatry · 2025Article
- Parvalbumin gates chronic pain through the modulation of firing patterns in inhibitory neurons.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The clustered gamma protocadherin PcdhγC4 isoform regulates cortical interneuron programmed cell death in the mouse cortex.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The function ofFrontiers in cellular neuroscience · 2024Review
- Human pallial MGE-type GABAergic interneuron cell therapy for chronic focal epilepsy.Cell stem cell · 2023Article
- Neonatal Maternal Separation Induces Sexual Dimorphism in Brain Development: The Influence on Amino Acid Levels and Cognitive Disorders.Biomolecules · 2023Article
- Developmental loss of ErbB4 in PV interneurons disrupts state-dependent cortical circuit dynamics.Molecular psychiatry · 2023Article
- Article
- Interneuron odyssey: molecular mechanisms of tangential migration.Frontiers in neural circuits · 2023Review
- Altered patterning of trisomy 21 interneuron progenitors.Stem cell reports · 2022Article
- Distinct neuronal excitability alterations of medial prefrontal cortex in early-life neglect model of rats.Animal models and experimental medicine · 2022Article
- Cell-Selective Adeno-Associated Virus-MediatedHuman gene therapy · 2022Article
- Chronic partial TrkB activation reduces seizures and mortality in a mouse model of Dravet syndrome.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Thyroid Hormone Transporter Deficiency in Mice Impacts Multiple Stages of GABAergic Interneuron Development.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Loss of ARHGAP15 affects the directional control of migrating interneurons in the embryonic cortex and increases susceptibility to epilepsy.Frontiers in cell and developmental biology · 2022Article
40 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A dysfunction of cortical and limbic GABAergic circuits has been postulated to contribute to multiple neurodevelopmental disorders in humans, including schizophrenia, autism, and epilepsy. In the current paper, I summarize the characteristics that underlie the great diversity of cortical GABAergic interneurons and explore how the multiple roles of these cells in developing and mature circuits might contribute to the aforementioned disorders. Furthermore, I review the tightly controlled genetic cascades that determine the fate of cortical interneurons and summarize how the dysfunction of genes important for the generation, specification, maturation, and function of cortical interneurons might contribute to these disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.