ArticleJournal of aging research2011
Stroke in the very old: a systematic review of studies on incidence, outcome, and resource use.
Article in Journal of aging research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Value of temporal muscle thickness in predicting outcomes of stroke: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Is endovascular treatment still good for acute ischemic stroke in the elderly? A meta-analysis of observational studies in the last decade.Frontiers in neuroscience · 2023Pooled it
- A randomized controlled trial of motor imagery combined with structured progressive circuit class therapy on gait in stroke survivors.Scientific reports · 2020Trial
- Venous Blood Cell Ratios as Predictors of Reperfusion Outcomes in Ischemic Stroke: A Systematic Review and Meta-analysis.Neurology and therapy · 2026Article
- Achieving complete recanalization is the best predicting factor of good outcome for thrombectomy in the elderly. Results from a prospective monocentric study.Acta neurologica Belgica · 2026Article
- Editorial: Stroke research in the elderly: addressing ageism and prognostication.Frontiers in stroke · 2026Article
- Edoxaban versus Apixaban Outcomes Differences in 8,444 Patients with Atrial Fibrillation from Italy: A Real-World Use Comparison.TH open : companion journal to thrombosis and haemostasis · 2026Article
- Should octogenarians and people aged 90 years and over be treated separately in studies of stroke? An evaluation of national audit data.Age and ageing · 2025Article
- Article
- Factors Associated With Premature Termination of Hyperacute Stroke Trials: A Review.Journal of the American Heart Association · 2024Review
- Barriers to Enrollment in a Post-Stroke Neuromodulation and Walking Study: Implications for Recruiting Women.Neurorehabilitation and neural repair · 2024Article
- Outcomes in elderly patients undergoing endovascular thrombectomy in association with premorbid Rankin Scale scores.Frontiers in neurology · 2024Article
- Exploring the Impact of Age and Pre-Stroke Modified Rankin Scale in Elderly Thrombectomy: A 15-Year Single-Center Experience.Cerebrovascular diseases extra · 2024Article
- Knowledge and Awareness of Stroke among the Elderly Population: Analysis of Data from a Sample of Older Adults in a Developing Country.Medicina (Kaunas, Lithuania) · 2023Article
- Metabolomics: A useful tool for ischemic stroke research.Journal of pharmaceutical analysis · 2023Review
- Stroke Thrombectomy in the Elderly: Efficacy, Safety, and Special Considerations.Stroke (Hoboken, N.J.) · 2023Review
- Clinical outcome and outcome prediction of octogenarians with acute basilar artery occlusion and endovascular stroke treatment compared to younger patients.Frontiers in neurology · 2023Article
- Patients with periodontitis are at a higher risk of stroke: A Taiwanese cohort study.Journal of the Chinese Medical Association : JCMA · 2022Article
- Sertad1 Induces Neurological Injury after Ischemic Stroke via the CDK4/p-Rb Pathway.Molecules and cells · 2022Article
- The Value of Contrast-Enhanced Ultrasound in the Evaluation of Carotid Web.Frontiers in neurology · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Purpose. Stroke incidence increases with age and is likely to increase in the aging populations. We investigated incidence, outcome, and resource use in very old subjects with stroke. Methods. We performed a systematic review of available data through electronic search of the literature databases and manual search of reference lists. Data were extracted for the age groups of over 80, 80 to 84 years old, and over 85. Overall incidence rates, expressed as the number of first strokes per 1000 person-years, were estimated using Poisson regression analysis. Odds ratios for the comparisons between subjects over and under 80 were calculated with the Mantel-Haenszel method. Results. We found a high incidence of stroke in the very old. The estimated incidence rates were 20.78 (95% CI 19.69 to 21.87) in subjects over 80, 17.23 (95% CI 15.97 to 18.49) for those 80 to 85 years old, and 20.78 (95% CI 16.74 to 23.78) for those over 85. Subjects over 80 contributed 29.95% of strokes; rates were similar among genders. Thirty-day case fatality rate and occurrence of dependency were higher in subjects over 80, although associated with less frequent hospital and stroke unit admission and less diagnostic resource use. Conclusions. The contribution of very old subjects to the global burden of stroke is relevant and may require efficient dedicated stroke services.
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Registered trials
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