ArticlePLoS genetics2011
Genetic architecture of a reinforced, postmating, reproductive isolation barrier between Neurospora species indicates evolution via natural selection.
Article in PLoS genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 51 citations in OpenAlex.
- A new family of ant-associated fungi inStudies in mycology · 2025Article
- Meiotic drive is associated with sexual incompatibility in Neurospora.Evolution; international journal of organic evolution · 2022Article
- Multilocus phylogenies reveal three new truffle-like taxa and the traces of interspecific hybridization in Octaviania (Boletaceae, Boletales).IMA fungus · 2021Article
- Meiotic recombination in the offspring of Microbotryum hybrids and its impact on pathogenicity.BMC evolutionary biology · 2020Article
- Review
- Diversity and Postzygotic Evolution of the Mitochondrial Genome in Hybrids ofFrontiers in microbiology · 2020Article
- Neurospora from Natural Populations: Population Genomics Insights into the Life History of a Model Microbial Eukaryote.Methods in molecular biology (Clifton, N.J.) · 2020Review
- Gene exchange between two divergent species of the fungal human pathogen, Coccidioides.Evolution; international journal of organic evolution · 2019Article
- The Rate of Evolution of Postmating-Prezygotic Reproductive Isolation in Drosophila.Molecular biology and evolution · 2018Article
- Mitonuclear interactions may contribute to fitness of fungal hybrids.Scientific reports · 2018Article
- Sources of Fungal Genetic Variation and Associating It with Phenotypic Diversity.Microbiology spectrum · 2017Review
- Article
- Rapid and widespread de novo evolution of kin discrimination.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Name changes in medically important fungi and their implications for clinical practice.Journal of clinical microbiology · 2015Article
- Discovery of a sexual cycle in Aspergillus lentulus, a close relative of A. fumigatus.Eukaryotic cell · 2013Article
- Genome wide association identifies novel loci involved in fungal communication.PLoS genetics · 2013Article
- Analyses of expressed sequence tags in Neurospora reveal rapid evolution of genes associated with the early stages of sexual reproduction in fungi.BMC evolutionary biology · 2012Article
- Article
- Colletotrichum - current status and future directions.Studies in mycology · 2012Article
- The Colletotrichum acutatum species complex.Studies in mycology · 2012Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A role for natural selection in reinforcing premating barriers is recognized, but selection for reinforcement of postmating barriers remains controversial. Organisms lacking evolvable premating barriers can theoretically reinforce postmating isolation, but only under restrictive conditions: parental investment in hybrid progeny must inhibit subsequent reproduction, and selected postmating barriers must restore parents' capacity to reproduce successfully. We show that reinforced postmating isolation markedly increases maternal fitness in the fungus Neurospora crassa, and we detect the evolutionary genetic signature of natural selection by quantitative trait locus (QTL) analysis of the reinforced barrier. Hybrid progeny of N. crassa and N. intermedia are highly inviable. Fertilization by local N. intermedia results in early abortion of hybrid fruitbodies, and we show that abortion is adaptive because only aborted maternal colonies remain fully receptive to future reproduction. In the first QTL analysis of postmating reinforcement in microbial eukaryotes, we identify 11 loci for abortive hybrid fruitbody development, including three major QTLs that together explain 30% of trait variance. One of the major QTLs and six QTLs of lesser effect are found on the mating-type determining chromosome of Neurospora. Several reinforcement QTLs are flanked by genetic markers showing either segregation distortion or non-random associations with alleles at other loci in a cross between N. crassa of different clades, suggesting that the loci also are associated with local effects on same-species reproduction. Statistical analysis of the allelic effects distribution for abortive hybrid fruitbody development indicates its evolution occurred under positive selection. Our results strongly support a role for natural selection in the evolution of reinforced postmating isolation in N. crassa.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.