ArticleAntimicrobial agents and chemotherapy2011
Spider venom peptides for gene therapy of Chlamydia infection.
Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Advances in the Role of Antimicrobial Peptides in the Management of Sexually Transmitted Infections.Journal of clinical laboratory analysis · 2025Review
- Nature's Arsenal: Uncovering Antibacterial Agents Against Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2025Review
- A review of the venom microbiome and its utility in ecology and evolution including future directions for emerging research.Symbiosis (Philadelphia, Pa.) · 2025Article
- Alternative strategies forFrontiers in microbiology · 2022Review
- Antimicrobials from Venomous Animals: An Overview.Molecules (Basel, Switzerland) · 2020Review
- Venom peptides in association with standard drugs: a novel strategy for combating antibiotic resistance - an overview.The journal of venomous animals and toxins including tropical diseases · 2020Review
- Anticancer, antimicrobial, and analgesic activities of spider venoms.Toxicology research · 2018Review
- Latarcins: versatile spider venom peptides.Cellular and molecular life sciences : CMLS · 2015Review
- Cyto-Insectotoxin 1a from Lachesana tarabaevi Spider Venom Inhibits Chlamydia trachomatis Infection.Probiotics and antimicrobial proteins · 2012Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spider venoms are vast natural pharmacopoeias selected by evolution. The venom of the ant spider Lachesana tarabaevi contains a wide variety of antimicrobial peptides. We tested six of them (latarcins 1, 2a, 3a, 4b, 5, and cytoinsectotoxin 1a) for their ability to suppress Chlamydia trachomatis infection. HEK293 cells were transfected with plasmid vectors harboring the genes of the selected peptides. Controlled expression of the transgenes led to a significant decrease of C. trachomatis viability inside the infected cells.
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Registered trials
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