ArticleJournal of women's health (2002)2011
The association of HIV status with bacterial vaginosis and vitamin D in the United States.
Article in Journal of women's health (2002), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The trial behind it
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- A blinded, randomized controlled trial of high-dose vitamin D supplementation to reduce recurrence of bacterial vaginosis.American journal of obstetrics and gynecology · 2014Trial
- Factors shaping vaginal microbiota long-term community dynamics in young adult women.Peer community journal · 2025Article
- The Prevalence, Antibiotic Resistance Pattern, and Associated Factors of Bacterial Vaginosis Among Women of the Reproductive Age Group from Felege Hiwot Referral Hospital, Ethiopia.Infection and drug resistance · 2021Article
- Associations between dietary micronutrient intake and molecular-Bacterial Vaginosis.Reproductive health · 2019Article
- Serum 25-Hydroxyvitamin D and Risk of Self-Reported Bacterial Vaginosis in a Prospective Cohort Study of Young African American Women.Journal of women's health (2002) · 2018Article
- Vitamin D deficiency and periodontal clinical attachment loss in HIV-seropositive women: A secondary analysis conducted in the Women's Interagency HIV Study (WIHS).Oral surgery, oral medicine, oral pathology and oral radiology · 2018Article
- Serum vitamin D status and bacterial vaginosis prevalence and incidence in Zimbabwean women.American journal of obstetrics and gynecology · 2016Article
- Evaluation of Health Disparity in Bacterial Vaginosis and the Implications for HIV-1 Acquisition in African American Women.American journal of reproductive immunology (New York, N.Y. : 1989) · 2016Review
- Bacterial vaginosis and season, a proxy for vitamin D status.Sexually transmitted diseases · 2014Article
- Vitamin D insufficiency may impair CD4 recovery among Women's Interagency HIV Study participants with advanced disease on HAART.AIDS (London, England) · 2013Article
- Relevance of vitamin D in reproduction.Human reproduction (Oxford, England) · 2012Review
- Association among vitamin D, oral candidiasis, and calprotectinemia in HIV.Journal of dental research · 2012Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo estimate the association between vitamin D deficiency and bacterial vaginosis (BV) among nonpregnant HIV-infected and uninfected women.
methodsIn a substudy of the Women's Interagency HIV Study, including women from Chicago and New York, the association between BV and vitamin D deficiency, demographics, and disease characteristics was tested using generalized estimating equations. Deficiency was defined as <20 ng/mL 25 (OH) vitamin D and insufficiency as >20 and ≤30 ng/mL. BV was defined by the Amsel criteria.
resultsAmong 602 observations of nonpregnant women (480 HIV infected and 122 uninfected), BV was found in 19%. Vitamin D deficiency was found in 59.4%, and insufficiency was found in 24.4%. In multivariable analysis, black race was the most significant predictor of BV (adjusted odds ratio [AOR] 5.90, (95% confidence interval [CI] 2.52-13.8). Vitamin D deficiency was independently associated with BV among HIV-infected women (AOR 3.12, 95% CI 1.16-8.38) but not among HIV-uninfected women. There was a negative linear correlation between vitamin D concentration and prevalence of BV in HIV-infected women (r=-0.15, p=0.001).
conclusionsVitamin D deficiency was very common in this cohort and significantly associated with BV among HIV-infected women. These preliminary findings suggest that further epidemiologic and mechanistic exploration of the relationship between vitamin D and BV in HIV-infected women is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.