Evidence map›Paper›PMID 21874158›Full record

ArticlePulmonary circulation2011

A consensus approach to the classification of pediatric pulmonary hypertensive vascular disease: Report from the PVRI Pediatric Taskforce, Panama 2011.

Maria Jesus Del Cerro, Steven Abman, Gabriel Diaz, Alexandra Heath Freudenthal, Franz Freudenthal, S Harikrishnan, Sheila G Haworth, Dunbar Ivy, Antonio A Lopes, J Usha Raj and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Pulmonary circulation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 1 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 1 synthesis or guideline pooled it, 267 citations in OpenAlex.

  1. Pooled it
  2. Phenotype-based screening algorithm for chronic pulmonary hypertension in preterm infants with bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  3. Review
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Diagnostic and therapeutic precision in cardiovascular diseases in the neonatal intensive care.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  9. Review
  10. Common shunt lesions with pulmonary hypertension-who will benefit from surgery?Indian journal of thoracic and cardiovascular surgery · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 9 countries.

Maria Jesus Del CerroLa Paz Children's Hospital, Madrid, Spain.
Steven Abman
Gabriel Diaz
Alexandra Heath Freudenthal
Franz Freudenthal
S Harikrishnan
Sheila G Haworth
Dunbar Ivy
Antonio A Lopes
J Usha Raj
Julio Sandoval
Kurt Stenmark
Ian Adatia
Children's Hospital Colorado · USInstituto Boliviano de Ciencia y Tecnología Nuclear · BOHospital Universitario La Paz · ESInstituto Nacional de Cardiología · MXSree Chitra Thirunal Institute for Medical Sciences and Technology · INStollery Children's Hospital · CAUniversidade de São Paulo · BRUniversidad Nacional de Colombia · COUniversity College London · GBUniversity of Chicago · US

Funding

Non-Invasive Inhaled NO in Premature NewbornsP50HL084923 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI STENMARK, KURT R. · 2007 to 2012
$11.2M
NHLBI NIH HHS P50 HL084923
6 · The paper itself

Abstract

Current classifications of pulmonary hypertension have contributed a great deal to our understanding of pulmonary vascular disease, facilitated drug trials, and improved our understanding of congenital heart disease in adult survivors. However, these classifications are not applicable readily to pediatric disease. The classification system that we propose is based firmly in clinical practice. The specific aims of this new system are to improve diagnostic strategies, to promote appropriate clinical investigation, to improve our understanding of disease pathogenesis, physiology and epidemiology, and to guide the development of human disease models in laboratory and animal studies. It should be also an educational resource. We emphasize the concepts of perinatal maladaptation, maldevelopment and pulmonary hypoplasia as causative factors in pediatric pulmonary hypertension. We highlight the importance of genetic, chromosomal and multiple congenital malformation syndromes in the presentation of pediatric pulmonary hypertension. We divide pediatric pulmonary hypertensive vascular disease into 10 broad categories.

Identifiers

PMID21874158
PMCPMC3161725
OpenAlexW1974058266

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.