Evidence map›Paper›PMID 21874145›Full record

ArticlePain management2011

Assessing pain in preterm infants in the neonatal intensive care unit: moving to a 'brain-oriented' approach.

Liisa Holsti, Ruth E Grunau, Eilon Shany

Registry-linked trialAbstract read
In one paragraph

Article in Pain management, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05080582 (Does Mother Scented Simulated Hand Promote Comfort, Reduce Pain and Distress Among Mechanically Ventilated Preterm Neonates During Invasive Procedures), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05080582 nacompletednot on this mapstarted 2021, after this paper: background citation

Does Mother Scented Simulated Hand Promote Comfort, Reduce Pain and Distress Among Mechanically Ventilated Preterm Neonates During Invasive Procedures

TypeinterventionalSponsorAlexandria UniversityRan2021 to 2021Enrolled62ConditionsPain, Distress, EmotionalArmsMother-Scented Simulated Hand, NICU Standard Care
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Pain in Preterm Infants: Different Perspectives.The Journal of perinatal education · 2021
    Article
  5. Review
  6. Neonatal Pain: Perceptions and Current Practice.Critical care nursing clinics of North America · 2018
    Review
  7. Observational
  8. Article
  9. Pain management in newborns.Clinics in perinatology · 2014
    Review
  10. Review
  11. Article
  12. Neonatal pain.Paediatric anaesthesia · 2014
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Liisa HolstiDevelopmental Neurosciences & Child Health, Child & Family Research Institute, Vancouver, Canada.
Ruth E Grunau
Eilon Shany

Funding

PAIN IN PRETERM INFANTS--DEVELOPMENT AND EFFECTSR01HD039783 · NICHD · UNIVERSITY OF BRITISH COLUMBIA · PI GRUNAU, RUTH E · 2001 to 2012
$1.8M
NICHD NIH HHS R01 HD039783
6 · The paper itself

Abstract

Preterm infants in the neonatal intensive care unit undergo repeated exposure to procedural and ongoing pain. Early and long-term changes in pain processing, stress-response systems and development may result from cumulative early pain exposure. So that appropriate treatment can be given, accurate assessment of pain is vital, but is also complex because these infants' responses may differ from those of full-term infants. A variety of uni- and multidimensional assessment tools are available; however, many have incomplete psychometric testing and may not incorporate developmentally important cues. Near-infrared spectroscopy and/or EEG techniques that measure neonatal pain responses at a cortical level offer new opportunities to validate neonatal pain assessment tools.

Identifiers

PMID21874145
PMCPMC3161414

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.