Evidence map›Paper›PMID 21874061›Full record

Trial reportBone marrow transplantation2012

Ustekinumab demonstrates activity in glucocorticoid-refractory acute GVHD.

J Pidala, L Perez, F Beato, C Anasetti

Abstract readCase ReportsClinical Trial, Phase IILetter
PubMed Publisher
In one paragraph

Trial report in Bone marrow transplantation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Haematologica · 2018
    Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. IL-17A ≠ Th17 in GvHD.Cellular & molecular immunology · 2018
    Article
  8. Targeting JAK2 reduces GVHD and xenograft rejection through regulation of T cell differentiation.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  9. Review
  10. Article
  11. Review
  12. Essential Role of Interleukin-12/23p40 in the Development of Graft-versus-Host Disease in Mice.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2015
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

J Pidala
L Perez
F Beato
C Anasetti

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI KENNETH Lynn WRIGHT · 1998 to 2026
$93.5M
Antigen Specific T Cell tolerance by Anti CD3 AntibodiesR01CA132197 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI ANASETTI, CLAUDIO · 2008 to 2012
$1.8M
Peripheral T Cell tolerance by targeting AKTR21AI082498 · NIAID · H. LEE MOFFITT CANCER CTR & RES INST · PI ANASETTI, CLAUDIO · 2009 to 2010
$459k
NCI NIH HHS CA076292NCI NIH HHS CA132197NCI NIH HHS R01 CA132197NIAID NIH HHS AI082498
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedDrug ResistanceFemaleGlucocorticoidsGraft vs Host DiseaseHumansProteinsUstekinumabAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedGlucocorticoidsimmunosuppressive 40 kDa protein, ratProteinsUstekinumab

Identifiers

PMID21874061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.