Evidence map›Paper›PMID 21873834›Full record

ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2011

Depressive symptoms and functional transitions over time in older persons.

Lisa C Barry, Terrence E Murphy, Thomas M Gill

Abstract read
In one paragraph

Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Factors associated with functional loss among community-dwelling Mexican older adults.Biomedica : revista del Instituto Nacional de Salud · 2020
    Article
  8. Article
  9. Observational
  10. Review
  11. Cohort Profile: The Precipitating Events Project (PEP Study).The journal of nutrition, health & aging · 2020
    Article
  12. Article
  13. Symptomatic and functional recovery in depression in later life.Social psychiatry and psychiatric epidemiology · 2018
    Article
  14. Article
  15. Article
  16. Article
  17. Late-life depression and cardiovascular disease burden: examination of reciprocal relationship.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2014
    Article
  18. Relative effectiveness of reappraisal and distraction in regulating emotion in late-life depression.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2014
    Article
  19. Review
  20. Are depression and frailty overlapping syndromes in mid- and late-life? A latent variable analysis.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lisa C BarryDepartment of Internal Medicine, Yale University School of Medicine, Yale University, New Haven, CT 06520, USA. lisa.barry@yale.edu
Terrence E Murphy
Thomas M Gill

Funding

Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
Epidemiology of Disability and Recovery in Older PersonsR37AG017560 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2005 to 2014
$7.3M
Epidemiology of Bathing Disability in Elderly PersonsR01AG022993 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2004 to 2007
$1.6M
Research Training in Disability &Disabling DisordersK24AG021507 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2003 to 2012
$1.6M
Depression and Disability in Older Persons: Untangling ComplexitiesK01AG031324 · NIA · YALE UNIVERSITY · PI BARRY, LISA C · 2008 to 2012
$618k
NIA NIH HHS K01 AG031324NIA NIH HHS K01AG031324NIA NIH HHS K24 AG021507NIA NIH HHS K24AG021507NIA NIH HHS P30 AG021342NIA NIH HHS P30AG21342NIA NIH HHS R01 AG022993NIA NIH HHS R01AG022993NIA NIH HHS R37 AG017560NIA NIH HHS R37AG17560
6 · The paper itself

Abstract

objectiveThe authors determined the association between clinically significant depressive symptoms, often referred to as depression, and subsequent transitions between no disability, mild disability, severe disability, and death.

designProspective cohort study.

settingGeneral community in greater New Haven, Connecticut, from March 23, 1998, to December 31, 2008.

participantsSeven hundred fifty-four persons, age 70 years or older. MEASUREMENTS: Monthly assessments of disability in essential activities of daily living and assessments of depressive symptoms every 18 months using a short-form of the Center for Epidemiologic Studies of Depression Scale for up to 129 months.

resultsDepressed participants were more likely than those who were nondepressed to transition from a state of no disability to mild (HR = 1.52; 95% CI: 1.25-1.85) and severe disability (HR = 1.57; 95% CI: 1.22-2.01), and from a state of mild disability to severe disability (HR = 1.33; 95% CI: 1.06-1.65), and were less likely to transition from a state of mild disability to no disability (HR = 0.69; 95% CI: 0.57-0.85) and from a state of severe disability to no disability (HR = 0.50; 95% CI: 0.31-0.79).

conclusionsDepressive symptoms are associated with transitions into and out of disabled states and with increased likelihood of transitioning from mild to severe disability. More broadly, our findings underscore the complexity of the relationship between depressive symptoms and disability. Future work is needed to evaluate the likely reciprocal relationship between depression and functional transitions in older persons.

Indexed as

Activities of Daily LivingAgedAgingCohort StudiesDepressionDisability EvaluationFemaleHumansMaleProspective StudiesPsychiatric Status Rating Scales

Identifiers

PMID21873834
PMCPMC3164788

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.