ReviewSchizophrenia bulletin2011
Bleuler and the neurobiology of schizophrenia.
Review in Schizophrenia bulletin, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Peripheral Blood-Based Gene Expression Studies in Schizophrenia: A Systematic Review.Frontiers in genetics · 2021Pooled it
- Static and Dynamic Dysconnectivity in Early Psychosis: Relationship With Symptom Dimensions.Schizophrenia bulletin · 2024Article
- Homogenization of word relationships in schizophrenia: Topological analysis of cortical semantic representations.Psychiatry and clinical neurosciences · 2024Article
- Disorganization of Semantic Brain Networks in Schizophrenia Revealed by fMRI.Schizophrenia bulletin · 2023Article
- Natural Language Processing: Its Potential Role in Clinical Care and Clinical Research.Schizophrenia bulletin · 2022Article
- History of ECT in Schizophrenia: From Discovery to Current Use.Schizophrenia bulletin open · 2022Article
- Schizophrenia, the gut microbiota, and new opportunities from optogenetic manipulations of the gut-brain axis.Behavioral and brain functions : BBF · 2021Review
- Cognition and Reward Circuits in Schizophrenia: Synergistic, Not Separate.Biological psychiatry · 2020Review
- Schizophrenia, Not a Psychotic Disorder: Bleuler Revisited.Frontiers in psychiatry · 2019Review
- Racial disparities in bipolar disorder treatment and research: a call to action.Bipolar disorders · 2018Review
- An Update on Promising Biomarkers in Schizophrenia.Focus (American Psychiatric Publishing) · 2018Review
- Altered prefrontal activity and connectivity predict different cognitive deficits in schizophrenia.Human brain mapping · 2015Article
- [Schizophrenia and other psychotic disorders in DSM-5: summary of the changes compared to DSM-IV].Der Nervenarzt · 2014Article
- Ventral striatum gray matter density reduction in patients with schizophrenia and psychotic emotional dysregulation.NeuroImage. Clinical · 2014Article
- Graph-based network analysis in schizophrenia.World journal of psychiatry · 2012Article
- Faulty suppression of irrelevant material in patients with thought disorder linked to attenuated frontotemporal activation.Schizophrenia research and treatment · 2012Article
- Eugen Bleuler and the schizophrenias: 100 years after.Schizophrenia bulletin · 2011Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Schizophrenia remains a major challenge for psychiatry. One hundred years after the publication of Eugen Bleuler's monograph, we are still debating the nosology and mechanisms of schizophrenia. We have stalled in the development of more effective treatments, after success with the introduction of antipsychotic medication. Cure and prevention remain in the distance. This article reviews the importance of Bleuler's monograph for the neuroscientific exploration of schizophrenia. While Bleuler assumed that schizophrenia has a neural basis, he remained agnostic on possible mechanisms and skeptical about the value of pathological diagnosis. He preferred psychological understanding over neural explanation. He gave hope by making schizophrenia dimensional and less predictive of course and outcome. To make progress now, we need to redefine schizophrenia at the level of the brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.