ArticleApplied and environmental microbiology2011
Spontaneous Gac mutants of Pseudomonas biological control strains: cheaters or mutualists?
Article in Applied and environmental microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 48 citations in OpenAlex.
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- Enforced specialization fosters mutual cheating and not division of labour in the bacterium Pseudomonas aeruginosa.Journal of evolutionary biology · 2022Article
- The Type VI Secretion Systems in Plant-Beneficial Bacteria Modulate Prokaryotic and Eukaryotic Interactions in the Rhizosphere.Frontiers in microbiology · 2022Article
- Delving into defence: identifying theMicrobial genomics · 2021Article
- Bacterial siderophores in community and host interactions.Nature reviews. Microbiology · 2020Review
- Positive linkage between bacterial social traits reveals that homogeneous rather than specialised behavioral repertoires prevail in natural Pseudomonas communities.FEMS microbiology ecology · 2020Article
- Privatization of public goods can cause population decline.Nature ecology & evolution · 2019Article
- Polyamine is a critical determinant of Pseudomonas chlororaphis O6 for GacS-dependent bacterial cell growth and biocontrol capacity.Molecular plant pathology · 2018Article
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- Predator-by-Environment Interactions Mediate Bacterial Competition in theFrontiers in microbiology · 2018Article
- The path to re-evolve cooperation is constrained in Pseudomonas aeruginosa.BMC evolutionary biology · 2017Article
- Pseudomonas chlororaphis Produces Two Distinct R-Tailocins That Contribute to Bacterial Competition in Biofilms and on Roots.Applied and environmental microbiology · 2017Article
- Lack of Ecological and Life History Context Can Create the Illusion of Social Interactions in Dictyostelium discoideum.PLoS computational biology · 2016Article
- Beyond the Black Queen Hypothesis.The ISME journal · 2016Review
- Virulence determinants of Pseudomonas syringae strains isolated from grasses in the context of a small type III effector repertoire.BMC microbiology · 2014Article
- The requirement for the LysR-type regulator PtrA for Pseudomonas chlororaphis PA23 biocontrol revealed through proteomic and phenotypic analysis.BMC microbiology · 2014Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteria rely on a range of extracellular metabolites to suppress competitors, gain access to resources, and exploit plant or animal hosts. The GacS/GacA two-component regulatory system positively controls the expression of many of these beneficial external products in pseudomonad bacteria. Natural populations often contain variants with defective Gac systems that do not produce most external products. These mutants benefit from a decreased metabolic load but do not appear to displace the wild type in nature. How could natural selection maintain the wild type in the presence of a mutant with enhanced growth? One hypothesis is that Gac mutants are "cheaters" that do not contribute to the public good, favored within groups but selected against between groups, as groups containing more mutants lose access to ecologically important external products. An alternative hypothesis is that Gac mutants have a mutualistic interaction with the wild type, so that each variant benefits by the presence of the other. In the biocontrol bacterium Pseudomonas chlororaphis strain 30-84, Gac mutants do not produce phenazines, which suppress competitor growth and are critical for biofilm formation. Here, we test the predictions of these alternative hypotheses by quantifying interactions between the wild type and the phenazine- and biofilm-deficient Gac mutant within growing biofilms. We find evidence that the wild type and Gac mutants interact mutualistically in the biofilm context, whereas a phenazine-defective structural mutant does not. Our results suggest that the persistence of alternative Gac phenotypes may be due to the stabilizing role of local mutualistic interactions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.