ArticleJournal of the American Medical Informatics Association : JAMIA2012
Implementation of a deidentified federated data network for population-based cohort discovery.
Article in Journal of the American Medical Informatics Association : JAMIA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- The Detection of Date Shifting in Real-World Data.Applied clinical informatics · 2023Article
- Developing and testing a protocol using a common data model for federated collection and analysis of national perinatal health indicators in Europe.Open research Europe · 2023Article
- EHR-based cohort assessment for multicenter RCTs: a fast and flexible model for identifying potential study sites.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- ACE: the Advanced Cohort Engine for searching longitudinal patient records.Journal of the American Medical Informatics Association : JAMIA · 2021Article
- What You Need to Know Before Implementing a Clinical Research Data Warehouse: Comparative Review of Integrated Data Repositories in Health Care Institutions.JMIR formative research · 2020Review
- Scale-up of the Accrual to Clinical Trials (ACT) network across the Clinical and Translational Science Award Consortium: a mixed-methods evaluation of the first 18 months.Journal of clinical and translational science · 2020Article
- Characterizing Basic and Complex Usage of i2b2 at an Academic Medical Center.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020Article
- Leaf: an open-source, model-agnostic, data-driven web application for cohort discovery and translational biomedical research.Journal of the American Medical Informatics Association : JAMIA · 2020Article
- Accrual to Clinical Trials (ACT): A Clinical and Translational Science Award Consortium Network.JAMIA open · 2018Article
- Implementing partnership-driven clinical federated electronic health record data sharing networks.International journal of medical informatics · 2016Article
- Facilitating biomedical researchers' interrogation of electronic health record data: Ideas from outside of biomedical informatics.Journal of biomedical informatics · 2016Review
- Feasibility of Representing Data from Published Nursing Research Using the OMOP Common Data Model.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2016Article
- Modular design, application architecture, and usage of a self-service model for enterprise data delivery: the Duke Enterprise Data Unified Content Explorer (DEDUCE).Journal of biomedical informatics · 2014Article
- Expanding assessments of translational research programs: supplementing metrics with value judgments.Evaluation & the health professions · 2014Article
- Mission and Sustainability of Informatics for Integrating Biology and the Bedside (i2b2).EGEMS (Washington, DC) · 2014Article
- Sustaining Research Networks: the Twenty-Year Experience of the HMO Research Network.EGEMS (Washington, DC) · 2014Article
- Federated queries of clinical data repositories: the sum of the parts does not equal the whole.Journal of the American Medical Informatics Association : JAMIA · 2013Article
- Ancillary study management systems: a review of needs.BMC medical informatics and decision making · 2013Article
- Article
- Desiderata for healthcare integrated data repositories based on architectural comparison of three public repositories.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThe Cross-Institutional Clinical Translational Research project explored a federated query tool and looked at how this tool can facilitate clinical trial cohort discovery by managing access to aggregate patient data located within unaffiliated academic medical centers.
methodsThe project adapted software from the Informatics for Integrating Biology and the Bedside (i2b2) program to connect three Clinical Translational Research Award sites: University of Washington, Seattle, University of California, Davis, and University of California, San Francisco. The project developed an iterative spiral software development model to support the implementation and coordination of this multisite data resource.
resultsBy standardizing technical infrastructures, policies, and semantics, the project enabled federated querying of deidentified clinical datasets stored in separate institutional environments and identified barriers to engaging users for measuring utility. DISCUSSION: The authors discuss the iterative development and evaluation phases of the project and highlight the challenges identified and the lessons learned.
conclusionThe common system architecture and translational processes provide high-level (aggregate) deidentified access to a large patient population (>5 million patients), and represent a novel and extensible resource. Enhancing the network for more focused disease areas will require research-driven partnerships represented across all partner sites.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.