Evidence map›Paper›PMID 21873419›Full record

GuidelineEuropean heart journal2011

ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC).

Christian W Hamm, Jean-Pierre Bassand, Stefan Agewall, Jeroen Bax, Eric Boersma, Hector Bueno, Pio Caso, Dariusz Dudek, Stephan Gielen, Kurt Huber and 8 more

9 registry-linked trialsAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in European heart journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 917 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
917citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03329729 completedstarted 2018, after this paper: background citation

Non-interventional, Multicenter Clinical Trial to Investigate the Efficacy of Rosuvastatin in Patients With Hyperlipidemia and Other Cardiovascular Risk Factors.

Ran2018Enrolled4,700Registered outcomes3Posted comparisons0ConditionsDyslipidemias, Hyperlipidemias, Quality of Life, Risk Factor, CardiovascularArmsRosuvastatin
Open the trial in the graph
NCT01764334 phase4unknown statusnot on this map

A Developmental Clinical Study of Management Guided by Coronary Angiography Combined With Fractional Flow Reserve (FFR) Measurement Versus Management Guided by Coronary Angiography Alone(Standard Care) in Patients With Non-ST Elevation MI.

TypeinterventionalSponsorNHS National Waiting Times Centre BoardRan2011 to 2020Enrolled350ConditionsNonST Elevation Myocardial Infarction, Myocardial InfarctionArmsFractional flow reserve
NCT02317445 completednot on this map

Beijing Tiantan Hospital,Capital Medical University.

TypeobservationalSponsorCapital Medical UniversityRan2008 to 2013Enrolled472ConditionsAcute Coronary Syndrome
NCT02543177 naterminatednot on this mapstarted 2015, after this paper: background citation

Optimised Procedure in Patients With an Acute Non-ST-segment Elevation Myocardial Infarction and Acute or Chronic Kidney Disease

TypeinterventionalSponsorRWTH Aachen UniversityRan2015 to 2018Enrolled1ConditionsNon-ST-segment Elevation Myocardial Infarction, Chronic Kidney DiseaseArmscoronary angiography, ischemic precondition, prior kidney irrigation
NCT02648113 nacompletednot on this mapstarted 2016, after this paper: background citation

Cost-effectiveness and Cost-utility of Liberal vs Restrictive Red Blood Cell Transfusion Strategies in Patients With Acute Myocardial Infarction and Anaemia. The REALITY (REstrictive And LIberal Transfusion Strategies in Patients With Acute mYocardial Infarction) Randomized Trial.

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2016 to 2020Enrolled668ConditionsMyocardial Infarction, Anemia, Blood TransfusionArmsRestrictive transfusion, Liberal transfusion, red blood transfusion
NCT02748330 phase4completednot on this mapstarted 2016, after this paper: background citation

A Randomized, Open-label, Active-controlled, Parallel-group Study to Investigate the Platelet Inhibition of Ticagrelor Versus Clopidogrel in Patients With Stable Coronary Artery Disease and Type 2 Diabetes Mellitus After Recent Elective Percutaneous Coronary Intervention

TypeinterventionalSponsorPeking Union Medical College HospitalRan2016 to 2018Enrolled40ConditionsCoronary Artery Disease, Diabetes Mellitus, Type 2ArmsTicagrelor, Clopidogrel, Aspirin
NCT03347435 naterminatednot on this mapstarted 2013, after this paper: background citation

Pharmacogenetics of Clopidogrel in Acute Coronary Syndromes

TypeinterventionalSponsorAzienda Ospedaliero-Universitaria di ParmaRan2013 to 2015Enrolled889ConditionsAcute Coronary SyndromesArmsgenetic tests for CYP2C19*2, CYP2C19*17 and ABCB1 3435, clinical algorithm
NCT03881943 phase4completednot on this mapstarted 2017, after this paper: background citation

A Randomized, Single Center Trial to Assess the Endothelial Function With Ticagrelor Monotherapy Compared to Aspirin Monotherapy in Patients With History of Acute Coronary Syndrome

TypeinterventionalSponsorThe University of Hong KongRan2017 to 2018Enrolled200ConditionsAcute Coronary SyndromeArmsTicagrelor 60 mg, Aspirin 100 MG Oral Tablet, Enteric Coated
NCT05902117 nacompletednot on this mapstarted 2023, after this paper: background citation

Place of Copeptin-troponin Assay in the Elimination Diagnosis of Non-ST+ ACS in the Management of Pre-hospital and In-hospital Non-traumatic Chest Pain in Adults

TypeinterventionalSponsorHôpital NOVORan2023 to 2025Enrolled270ConditionsAcute Myocardial InfarctionArmsTroponin and Copeptin assay
3 · Its place in the literature

Who cites it

917 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Safety and Efficacy of Cangrelor in Acute Coronary Syndromes: A Systematic Review and Network Meta-Analysis.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024
    Pooled it
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  6. Early vs. Delayed Initiation of Treatment With P2YFrontiers in cardiovascular medicine · 2022
    Pooled it
  7. Management of Spontaneous Isolated Mesenteric Artery Dissection: A Systematic Review.Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society · 2021
    Pooled it
  8. Management of Acute Mesenteric Venous Thrombosis: A Systematic Review of Contemporary Studies.Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society · 2021
    Pooled it
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  12. Trial
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  19. Association of CYP2C19 Polymorphism with Clopidogrel Resistance in Patients with Acute Coronary Syndrome in China.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Trial
  20. Review

857 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Christian W HammKerckhoff Heart and Thorax Center, Germany. c.hamm@kerckhoff-klinik.de
Jean-Pierre Bassand
Stefan Agewall
Jeroen Bax
Eric Boersma
Hector Bueno
Pio Caso
Dariusz Dudek
Stephan Gielen
Kurt Huber
Magnus Ohman
Mark C Petrie
Frank Sonntag
Miguel Sousa Uva
Robert F Storey
William Wijns
Doron Zahger
ESC Committee for Practice Guidelines

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Coronary SyndromeAgedAged, 80 and overAge FactorsAngioplasty, Balloon, CoronaryAnticoagulantsBiomarkersCardiotonic AgentsCoronary Artery BypassDiabetic CardiomyopathiesDiagnosis, DifferentialDiagnostic ImagingEvidence-Based MedicineFemaleHemorrhageHumansAnticoagulantsBiomarkersCardiotonic AgentsPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa Complex

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 3 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.