ReviewEpilepsy research2012
Neuroprotection in metabolism-based therapy.
Review in Epilepsy research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 39 citations in OpenAlex.
- Cognitive Effects of a Ketogenic Diet on Neurocognitive Impairment in Adults Aging With HIV: A Pilot Study.The Journal of the Association of Nurses in AIDS Care : JANACTrial
- Daytime-Restricted Feeding Ameliorates Oxidative Stress by Increasing NRF2 Transcriptional Factor in the Rat Hippocampus in the Pilocarpine-Induced Acute Seizure Model.Brain sciences · 2023Article
- Role of nutritional ketosis in the improvement of metabolic parameters following bariatric surgery.World journal of diabetes · 2022Article
- Effects of Prolonged Intermittent Fasting Model on Energy Metabolism and Mitochondrial Functions in Neurons.Annals of neurosciences · 2022Article
- Ketogenic diet, neuroprotection, and antiepileptogenesis.Epilepsy research · 2020Review
- Metabolic switching is impaired by aging and facilitated by ketosis independent of glycogen.Aging · 2020Article
- The Effects of Meal Timing and Frequency, Caloric Restriction, and Fasting on Cardiovascular Health: an Overview.Journal of lipid and atherosclerosis · 2020Review
- Age-related changes in 'hub' neurons.Aging · 2018Article
- Non-invasive assessment of disease progression and neuroprotective effects of dietary coconut oil supplementation in the ALS SOD1NeuroImage. Clinical · 2018Article
- Nutritional Ketosis and Mitohormesis: Potential Implications for Mitochondrial Function and Human Health.Journal of nutrition and metabolism · 2018Review
- Cerebral Ketone Body Oxidation Is Facilitated by a High Fat Diet Enriched with Advanced Glycation End Products in Normal and Diabetic Rats.Frontiers in neuroscience · 2016Article
- Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy.Frontiers in molecular neuroscience · 2016Review
- Excitotoxic glutamate insults block autophagic flux in hippocampal neurons.Brain research · 2014Article
- Article
- Nutrition and the biology of human ageing: cognitive decline/food intake and caloric restriction.The journal of nutrition, health & aging · 2013Article
- The New Ketone Alphabet Soup: BHB, HCA, and HDAC.Epilepsy currentsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Metabolism-based therapy has been used successfully in the treatment of seizures but study of its use in other neurodegenerative disorders is growing. Data demonstrating the use of different forms of metabolism-based therapy in human trials of Alzheimer disease and Parkinson disease are discussed. Animal and in vitro studies have shed light on metabolism-based therapy's mechanisms in these diseases, as well as ALS, aging, ischemia, trauma and mitochondrial cytopathies. Additional insights may be obtained by considering the role of metabolism-based therapy in cell disability and death (specifically apoptosis, excitotoxicity, and autophagy).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.