Evidence map›Paper›PMID 21871816›Full record

ReviewCytokine2012

The role of cytokines and chemokines in Histoplasma capsulatum infection.

Danielle N Kroetz, George S Deepe

Abstract readReview
In one paragraph

Review in Cytokine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Review
  2. Review
  3. Usefulness of Serum as a Non-Invasive Sample for the Detection ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  4. Utilization of amSphere · 2024
    Article
  5. Common virulence factors betweenCurrent research in microbial sciences · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Danielle N KroetzDivision of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. kroetzdn@ucmail.uc.edu
George S Deepe

Funding

Immunopathogenesis in HistoplasmosisR01AI073337 · NIAID · UNIVERSITY OF CINCINNATI · PI DEEPE, GEORGE S. · 2008 to 2012
$2.0M
Chemokine-Cytokine Nexus in Fungal ImmunityR01AI083313 · NIAID · UNIVERSITY OF CINCINNATI · PI DEEPE, GEORGE S. · 2010 to 2014
$1.9M
Myeloid Cell KLF2 and IL-4 in HistoplasmosisR21AI096823 · NIAID · UNIVERSITY OF CINCINNATI · PI DEEPE, GEORGE S. · 2011 to 2012
$443k
GM-CSF Regulation of Zinc in HistoplasmosisR21AI094971 · NIAID · UNIVERSITY OF CINCINNATI · PI DEEPE, GEORGE S. · 2011 to 2012
$432k
Chemokine-Cytokine Nexus in Fungal ImmunityR56AI083313 · NIAID · UNIVERSITY OF CINCINNATI · PI DEEPE, GEORGE S. · 2009 to 2009
$294k
Molecular and Cellular Determinants of Immunity to HistoplasmosisI01BX000717 · VA · CINCINNATI VA MEDICAL CENTER RESEARCH · PI DEEPE, GEORGE S. · 2011 to 2017
–
BLRD VA I01 BX000717NIAID NIH HHS AI-073337NIAID NIH HHS AI-083313NIAID NIH HHS AI-094971NIAID NIH HHS AI-096823NIAID NIH HHS R01 AI073337NIAID NIH HHS R01 AI083313NIAID NIH HHS R21 AI094971NIAID NIH HHS R21 AI096823NIAID NIH HHS R56 AI083313
6 · The paper itself

Abstract

Histoplasma capsulatum is a prevalent fungal pathogen in the United States, infecting approximately 500,000 individuals each year. Host protection requires an intact cell-mediated immune response. In this review, we will discuss how cytokines and chemokines influence protective immunity in H. capsulatum infection.

Indexed as

AnimalsChemokinesCytokinesHistoplasmaHistoplasmosisHumansMiceReceptors, CCR5Th17 CellsTh1 CellsChemokinesCytokinesReceptors, CCR5

Identifiers

PMID21871816
PMCPMC3227768

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.