ArticleBiochemical and biophysical research communications2011
Decreased expression of ATP6V1H in type 2 diabetes: a pilot report on the diabetes risk study in Mexican Americans.
Article in Biochemical and biophysical research communications, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 24 citations in OpenAlex.
- Acidic Nanoparticles Restore Lysosomal Acidification and Rescue Metabolic Dysfunction in Pancreatic β-Cells under Lipotoxic Conditions.ACS nano · 2024Article
- Differential Transcriptome Profiling Unveils Novel Deregulated Gene Signatures Involved in Pathogenesis of Alzheimer's Disease.Biomedicines · 2022Article
- Article
- Understanding the growing epidemic of type 2 diabetes in the Hispanic population living in the United States.Diabetes/metabolism research and reviews · 2019Review
- ATP6V1H facilitates osteogenic differentiation in MC3T3-E1 cells via Akt/GSK3β signaling pathway.Organogenesis · 2019Article
- Genome-wide association study identified ATP6V1H locus influencing cerebrospinal fluid BACE activity.BMC medical genetics · 2018Article
- Protein homeostasis of a metastable subproteome associated with Alzheimer's disease.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Proteomic Profiling of Iron Overload-Induced Human Hepatic Cells Reveals Activation of TLR2-Mediated Inflammatory Response.Molecules (Basel, Switzerland) · 2016Article
- Host-pathogen interactions in tuberculosis patients with type 2 diabetes mellitus.Tuberculosis (Edinburgh, Scotland) · 2013Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
objectivePrevious studies in mice and humans observed down-regulation of the gene expression of ATP6V1H associated with type 2 diabetes. This study identified prospectively changes in ATP6V1H expression before and after overt diabetes.
methodsExpression of ATP6V1H in peripheral blood was compared pre and post development of diabetes in nine individuals.
resultsConsiderable variation of ATP6V1H mRNA levels was observed between different individuals. However, within each individual the decrease in expression of ATP6V1H with the development of diabetes was highly statistically significant.
conclusionsATP6V1H may represent a critical molecular mechanism involved in the development of type 2 diabetes and its compilations through its important regulatory effect on vacuolar-ATPase activity.
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