Evidence map›Paper›PMID 21871086›Full record

ArticleCritical care (London, England)2011

Admissions to intensive care unit of HIV-infected patients in the era of highly active antiretroviral therapy: etiology and prognostic factors.

Hou-Hsien Chiang, Chien-Ching Hung, Chang-Min Lee, Hsuan-Yu Chen, Mao-Yuan Chen, Wang-Huei Sheng, Szu-Min Hsieh, Hsin-Yun Sun, Chao-Chi Ho, Chong-Jen Yu

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  12. Scope and mortality of adult medical ICU patients in an Eastern Cape tertiary hospital.The Southern African journal of critical care : the official journal of the Critical Care Society · 2022
    Article
  13. Death-related factors in HIV/AIDS patients undergoing hemodialysis in an intensive care unit.Revista do Instituto de Medicina Tropical de Sao Paulo · 2021
    Article
  14. Review
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  18. Indian Antimicrobial Prescription Guidelines in Critically Ill Immunocompromised Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Hou-Hsien ChiangDepartment of Internal Medicine, Far East Memorial Hospital, Nanya South Road, New Taipei City 220, Taiwan.
Chien-Ching Hung
Chang-Min Lee
Hsuan-Yu Chen
Mao-Yuan Chen
Wang-Huei Sheng
Szu-Min Hsieh
Hsin-Yun Sun
Chao-Chi Ho
Chong-Jen Yu
National Taiwan University Hospital · TWAcademia Sinica · TWMemorial Hospital of South Bend · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough access to highly active antiretroviral therapy (HAART) has prolonged survival and improved life quality, HIV-infected patients with severe immunosuppression or comorbidities may develop complications that require critical care support in intensive care units (ICU). This study aimed to describe the etiology and analyze the prognostic factors of HIV-infected Taiwanese patients in the HAART era.

methodsMedical records of all HIV-infected adults who were admitted to ICU at a university hospital in Taiwan from 2001 to 2010 were reviewed to record information on patient demographics, receipt of HAART, and reason for ICU admission. Factors associated with hospital mortality were analyzed.

resultsDuring the 10-year study period, there were 145 ICU admissions for 135 patients, with respiratory failure being the most common cause (44.4%), followed by sepsis (33.3%) and neurological disease (11.9%). Receipt of HAART was not associated with survival. However, CD4 count was independently predictive of hospital mortality (adjusted odds ratio [AOR], per-10 cells/mm3 decrease, 1.036; 95% confidence interval [CI], 1.003 to 1.069). Admission diagnosis of sepsis was independently associated with hospital mortality (AOR, 2.91; 95% CI, 1.11 to 7.62). A hospital-to-ICU interval of more than 24 hours and serum albumin level (per 1-g/dl decrease) were associated with increased hospital mortality, but did not reach statistical significance in multivariable analysis.

conclusionsRespiratory failure was the leading cause of ICU admissions among HIV-infected patients in Taiwan. Outcome during the ICU stay was associated with CD4 count and the diagnosis of sepsis, but was not associated with HAART in this study.

Indexed as

Antiretroviral Therapy, Highly ActiveIntensive Care UnitsPatient AdmissionAdultComorbidityFemaleHIV InfectionsHospital MortalityHumansImmunocompromised HostMaleMedical AuditMiddle AgedNervous System DiseasesPrognosisRespiratory Insufficiency

Identifiers

PMID21871086
PMCPMC3387644
OpenAlexW2129875748

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.