ArticleThe Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics2011
Inclusion of racial and ethnic minorities in genetic research: advance the spirit by changing the rules?
Article in The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- A Systematic Review of DNA Methylation and Preterm Birth in African American Women.Biological research for nursing · 2017Pooled it
- Pharmacogenomic insights in psychiatric care: uncovering novel actionability, allele-specific CYP2D6 copy number variation, and phenoconversion in 15,000 patients.Molecular psychiatry · 2024Article
- Exploring the role of underrepresented populations in polygenic risk scores for neurodegenerative disease risk prediction.Frontiers in neuroscience · 2024Article
- Diagnosis and clinical presentation of two individuals with a rareBMJ case reports · 2022Article
- Targeting Representation: Interpreting Calls for Diversity in Precision Medicine Research.The Yale journal of biology and medicine · 2022Article
- Increasing access to individualized medicine: a matched-cohort study examining Latino participant experiences of genomic screening.Genetics in medicine : official journal of the American College of Medical Genetics · 2021Article
- Changing the Conversation about The Ethics of Genomics and Health Disparities Research with American Indian and Alaska Native Communities: A Report from the Field.Journal of health care for the poor and underserved · 2019Article
- Privacy and ethical challenges in next-generation sequencing.Expert review of precision medicine and drug development · 2019Article
- Linking Education to Action: A Program to Increase Research Participation Among African American Women.Journal of women's health (2002) · 2018Article
- Article
- Attitudes Toward Return of Genetic Research Results to Relatives, Including After Death: Comparison of Cancer Probands, Blood Relatives, and Spouse/Partners.Journal of empirical research on human research ethics : JERHRE · 2018Article
- Prostate Cancer Genomics: Recent Advances and the Prevailing Underrepresentation from Racial and Ethnic Minorities.International journal of molecular sciences · 2018Review
- Authorization of tissues from deceased patients for genetic research.Human genetics · 2018Article
- Self-reported race and ethnicity of US biobank participants compared to the US Census.Journal of community genetics · 2017Article
- Implementing Precision Medicine: The Ethical Challenges.Trends in pharmacological sciences · 2017Review
- A perspective for sequencing familial hypercholesterolaemia in African Americans.NPJ genomic medicine · 2016Article
- Demographic differences in willingness to provide broad and narrow consent for biobank research.Biopreservation and biobanking · 2015Article
- To Share or Not to Share? A Survey of Biomedical Researchers in the U.S. Southwest, an Ethnically Diverse Region.PloS one · 2015Article
- Physicians' knowledge, beliefs, and use of race and human genetic variation: new measures and insights.BMC health services research · 2014Article
- Recruitment and retention of African American and Hispanic girls and women in research.Public health nursing (Boston, Mass.) · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Genetic research aimed at understanding human health and disease is grounded in the study of genetic variation. The inclusion of research subjects with diverse ancestral backgrounds is essential for genetic and genomic research that fully explores human diversity. Large-scale cohort studies and biobanks in Europe and the United States often do not include the breadth of ethnic and racial diversity observed in their countries' citizens. This article explores the findings of a qualitative study of U.S. scientists' understanding and views of the NIH Policy and Guidelines on the Inclusion of Minorities as Subjects in Clinical Research. The findings suggest that the policy restricts how scientists use racial and ethnic categories to define and report their study populations and does little to motivate their efforts to increase the inclusion of non-European ancestral populations in genetic and genomic research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.