ArticleJournal of perinatology : official journal of the California Perinatal Association2012
White-gray matter echogenicity ratio and resistive index: sonographic bedside markers of cerebral hypoxic-ischemic injury/edema?
Article in Journal of perinatology : official journal of the California Perinatal Association, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- Cerebral resistive indices and intraventricular hemorrhage in premature neonates < 29 weeks' gestation: a pilot prospective cohort study.BMC pediatrics · 2025Article
- Transcranial Doppler sonography follow-up study in mild vascular cognitive impairment.PloS one · 2025Article
- Quantitative Evaluation of White Matter Injury by Cranial Ultrasound to Detect the Effects of Parenteral Nutrition in Preterm Babies: An Observational Study.Journal of imaging · 2024Article
- Ultrasound Diagnosis and Near-Infrared Spectroscopy in the Study of Encephalopathy in Neonates Born under Asphyxia: Narrative Review.Children (Basel, Switzerland) · 2024Review
- Quantitative ultrasonographic examination of cerebral white matter by pixel brightness intensity as marker of middle-term neurodevelopment: a prospective observational study.Scientific reports · 2023Observational
- Quantitative Evaluation of Brain Echogenicity in Hypoxic-Ischemic Encephalopathy in Term Neonates Compared with Controls.Ultrasound international open · 2022Article
- Using Doppler sonography resistive index for the diagnosis of perinatal asphyxia: a multi-centered study.BMC neurology · 2022Article
- Spectral-domain OCT changes in retina and optic nerve in children with hypoxic-ischaemic encephalopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Early postnatal color Doppler changes in neonates receiving delivery room resuscitation with low 5 min Apgar score-a pilot study.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- The development and validation of a cerebral ultrasound scoring system for infants with hypoxic-ischaemic encephalopathy.Pediatric research · 2020Article
- Ultrasound Predicts White Matter Integrity after Hypothermia Therapy in Neonatal Hypoxic-Ischemic Injury.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2019Article
- Normal values of the resistivity index of the pericallosal artery with and without compression of the anterior fontanelle.Pediatric radiology · 2019Article
- Evaluating a Targeted Bedside Measure of Cerebral Perfusion in a Nonhuman Primate Model of Neonatal Hypoxic-Ischemic Encephalopathy.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2018Article
- Noninvasive monitoring of brain edema after hypoxia in newborn piglets.Pediatric research · 2018Article
- Variability of resistive indices in the anterior cerebral artery during fontanel compression in preterm and term neonates measured by transcranial duplex sonography.Journal of perinatology : official journal of the California Perinatal Association · 2014Article
- Head Ultrasound Resistive Indices Are Associated With Brain Injury on Diffusion Tensor Imaging Magnetic Resonance Imaging in Neonates With Hypoxic-Ischemic Encephalopathy.Journal of computer assisted tomographyObservational
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveHead ultrasonography (HUS) is a reliable and easy to perform bedside imaging technique that can give valuable information about degree of brain injury/edema after perinatal asphyxia in term neonates. The goals of our study were to determine whether semiquantitative markers such as standardized white matter/gray matter (WM/GM) echogenicity ratio and resistive index (RI) value measured by HUS differs between asphyxiated term neonates and healthy controls. STUDY
designThirty-one carefully selected term neonates who suffered from perinatal hypoxic-ischemic encephalopathy (HIE) were included in the study. The ratio of the WM/GM echogenicity of the cingulate gyrus was calculated. In addition, the RI value was measured in the anterior cerebral artery. US scalars were compared with 11 healthy neonates.
resultWM/GM ratio is significantly increased and RI value significantly decreased in asphyxiated term neonates compared with healthy subjects.
conclusionWM/GM ratio and RI value allows discriminating between asphyxiated neonates and healthy subjects. These US scalars may serve as valuable, easy to acquire semiquantitative bedside markers of brain HIE, when magnetic resonance imaging is unavailable or cannot be performed in the acute setting.
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Registered trials
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