ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology1990
Value of detection of antibodies to Candida albicans germ tube in the diagnosis of systemic candidosis.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Diagnostic Potential of a Recombinant Candida albicans Hyr1 Protein.Mycopathologia · 2025Article
- Clinical factors associated with a Candida albicans Germ Tube Antibody positive test in Intensive Care Unit patients.BMC infectious diseases · 2011Article
- Use of recombinant antigens for the diagnosis of invasive candidiasis.Clinical & developmental immunology · 2008Review
- Diagnosis of invasive candidiasis by enzyme-linked immunosorbent assay using the N-terminal fragment of Candida albicans hyphal wall protein 1.BMC microbiology · 2007Article
- The detection of anti-Candida antibodies on experimental animal models.Folia microbiologica · 2003Article
- Detection of anti-Candida antibodies in neonates from a Neonatal Intensive Care Unit.Folia microbiologica · 2002Article
- Detection of anti-Candida antibodies by the indirect immunofluorescence assay in patients with cancer in the orofacial region.Folia microbiologica · 2002Article
- Use of monoclonal antibody in diagnosis of candidiasis caused by Candida albicans: detection of circulating aspartyl proteinase antigen.Clinical and diagnostic laboratory immunology · 1999Article
- Low levels of antigenic variability in fluconazole-susceptible and -resistant Candida albicans isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis.Clinical and diagnostic laboratory immunology · 1999Article
- Detection of antibodies to Candida albicans germ tubes during experimental infections by different Candida species.Clinical and diagnostic laboratory immunology · 1998Article
- Serologic response to cell wall mannoproteins and proteins of Candida albicans.Clinical microbiology reviews · 1998Review
- Detection of antibodies to Candida albicans germ tubes for diagnosis and therapeutic monitoring of invasive candidiasis in patients with hematologic malignancies.Journal of clinical microbiology · 1997Article
- Clinical and laboratory diagnosis of invasive candida infection in neutropenic patients.Medical oncology (Northwood, London, England) · 1996Review
- Re-expression by Candida albicans germ tubes of antigens lost during subculture of blastospores.Mycopathologia · 1996Article
- Evaluation of three serological tests for detection of anti-candidal antibodies in diagnosis of invasive candidiasis.Mycopathologia · 1994Article
- Simplified adsorption method for detection of antibodies to Candida albicans germ tubes.Journal of clinical microbiology · 1994Article
- Characterization of Candida albicans cell wall antigens with monoclonal antibodies.Infection and immunity · 1993Article
- Diagnosis of invasive mycoses in severely immunosuppressed patients.Annals of hematology · 1993Review
- Detection of antibodies to Candida albicans germ tube as a possible aid in diagnosing systemic candidiasis in bone marrow transplant patients.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 1993Article
- Identification of antigens reacting with anti-Candida albicans germ tube antibodies.European journal of epidemiology · 1992Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To test the value of detection of anti-Candida albicans germ tube antibodies by indirect immunofluorescence assay in the diagnosis of systemic candidosis, a retrospective study was done using 126 sera from 27 patients with presumptive systemic candidosis (13 immunocompromised), 165 sera from 45 patients with aspergillosis (29 immunocompromised), 35 sera from eight patients with cryptococcosis (6 immunocompromised), and 101 sera from 101 blood donors. While 21 of 27 patients with systemic candidosis (77.8%) had anti-germ tube antibodies, these antibodies were absent in all patients with cryptococcosis and in all blood donors. They were however detected in 5 of 45 patients with aspergillosis (11.1%). Ten of 13 (76.9%) immunocompromised patients with candidosis had anti-germ tube antibodies; similar results were obtained in immunocompetent patients with candidosis (78.6%). The specificity was 96.8%, indicating a high degree of discrimination was possible between systemic candidosis and other invasive mycoses in the patients studied. Anti-germ tube responses did not appear to be significantly reduced in immunocompromised patients.
Indexed as
Identifiers
2186911What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.